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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ssu72
Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)
MGI:1916241
18 phenotypes from 2 alleles in 2 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ssu72em1(IMPC)J/Ssu72+
C57BL/6NJ-Ssu72em1(IMPC)J/Mmjax 		decreased thigmotaxis J:211773
Ssu72em1(IMPC)J/Ssu72em1(IMPC)J
C57BL/6NJ-Ssu72em1(IMPC)J/Mmjax 		preweaning lethality, complete penetrance J:211773
Ssu72tm1Cwl/Ssu72tm1Cwl
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
B6.Cg-Ssu72tm1Cwl Speer6-ps1Tg(Alb-cre)21Mgn 		abnormal hepatocyte morphology J:309624
abnormal Ito cell morphology J:309624
abnormal liver development J:309624
abnormal liver morphology J:309624
hepatic necrosis J:309624
hepatic steatosis J:309624
increased circulating alanine transaminase level J:309624
increased circulating aspartate transaminase level J:309624
increased hepatocyte apoptosis J:309624
increased hepatocyte karyomegaly J:309624
increased hepatocyte proliferation J:309624
increased liver weight J:309624
increased physiological sensitivity to xenobiotic J:309624
liver fibrosis J:309624
liver inflammation J:309624
normal neoplasm J:309624
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory