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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Romo1
reactive oxygen species modulator 1
MGI:1914317
24 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Myl2tm1(cre)Krc/Myl2+
Romo1tm1Xiwa/Romo1tm1Xiwa
involves: 129S4/SvJae * C57BL/6
abnormal mitochondrial physiology J:367536
decreased oxygen consumption J:367536
Romo1em1(IMPC)Kmpc/Romo1+
C57BL/6NTac-Romo1em1(IMPC)Kmpc/Kmpc
hyperactivity J:211773
increased circulating creatine kinase level J:211773
increased circulating total protein level J:211773
Romo1em1(IMPC)Kmpc/Romo1em1(IMPC)Kmpc
C57BL/6NTac-Romo1em1(IMPC)Kmpc/Kmpc
abnormal embryo size J:211773
abnormal embryo turning J:211773
abnormal vitelline vasculature morphology J:211773
embryonic growth retardation J:211773
embryonic lethality prior to organogenesis J:211773
embryonic lethality prior to tooth bud stage J:211773
pale yolk sac J:211773
preweaning lethality, complete penetrance J:211773
Romo1tm1.1Xiwa/Romo1tm1.1Xiwa
involves: 129S4/SvJae * C57BL/6
prenatal lethality, complete penetrance J:367536
Romo1tm1Xiwa/Romo1tm1Xiwa
involves: 129S4/SvJae * C57BL/6
abnormal mitochondrial physiology J:367536
decreased oxygen consumption J:367536
Tg(CAG-Romo1)#Xiwa/0
involves: C57BL/6J
abnormal circulating lipoprotein level J:367536
abnormal liver physiology J:367536
abnormal mitochondrial physiology J:367536
abnormal muscle morphology J:367536
decreased circulating alanine transaminase level J:367536
decreased circulating aspartate transaminase level J:367536
decreased monocyte cell number J:367536
decreased neutrophil cell number J:367536
increased cardiac muscle contractility J:367536
increased grip strength J:367536
increased oxygen consumption J:367536

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory