Romo1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Romo1
reactive oxygen species modulator 1
MGI:1914317

24 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Myl2^tm1(cre)Krc/Myl2⁺ Romo1^tm1Xiwa/Romo1^tm1Xiwa involves: 129S4/SvJae * C57BL/6	abnormal mitochondrial physiology	J:367536
	decreased oxygen consumption	J:367536
Romo1^{em1(IMPC)Kmpc}/Romo1⁺ C57BL/6NTac-Romo1^{em1(IMPC)Kmpc}/Kmpc	hyperactivity	J:211773
	increased circulating creatine kinase level	J:211773
	increased circulating total protein level	J:211773
Romo1^{em1(IMPC)Kmpc}/Romo1^{em1(IMPC)Kmpc} C57BL/6NTac-Romo1^{em1(IMPC)Kmpc}/Kmpc	abnormal embryo size	J:211773
	abnormal embryo turning	J:211773
	abnormal vitelline vasculature morphology	J:211773
	embryonic growth retardation	J:211773
	embryonic lethality prior to organogenesis	J:211773
	embryonic lethality prior to tooth bud stage	J:211773
	pale yolk sac	J:211773
	preweaning lethality, complete penetrance	J:211773
Romo1^tm1.1Xiwa/Romo1^tm1.1Xiwa involves: 129S4/SvJae * C57BL/6	prenatal lethality, complete penetrance	J:367536
Romo1^tm1Xiwa/Romo1^tm1Xiwa involves: 129S4/SvJae * C57BL/6	abnormal mitochondrial physiology	J:367536
Romo1^tm1Xiwa/Romo1^tm1Xiwa involves: 129S4/SvJae * C57BL/6	decreased oxygen consumption	J:367536
Tg(CAG-Romo1)#Xiwa/0 involves: C57BL/6J	abnormal circulating lipoprotein level	J:367536
	abnormal liver physiology	J:367536
	abnormal mitochondrial physiology	J:367536
	abnormal muscle morphology	J:367536
	decreased circulating alanine transaminase level	J:367536
	decreased circulating aspartate transaminase level	J:367536
	decreased monocyte cell number	J:367536
	decreased neutrophil cell number	J:367536
	increased cardiac muscle contractility	J:367536
	increased grip strength	J:367536
	increased oxygen consumption	J:367536

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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