Use1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
MGI:1914273

14 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Use1^tm1.1Aha/Use1^tm1.1Aha involves: C57BL/6 * SJL	no abnormal phenotype detected	J:147771
Use1^tm1.1Aha/Use1^tm1.1Aha Tg(Nes-cre)1Kln/0 involves: C57BL/6 * SJL	abnormal brain physiology	J:147771
	abnormal neuron morphology	J:147771
	dilated brain ventricle	J:147771
	increased apoptosis	J:147771
	neonatal lethality	J:147771
	thin cerebral cortex	J:147771
Use1^tm1.1Aha/Use1^tm1.2Aha involves: BALB/cJ * C57BL/6 * SJL	abnormal endoplasmic reticulum morphology	J:147771
	increased endoplasmic reticulum stress	J:147771
	increased fibroblast apoptosis	J:147771
Use1^tm1.1Aha/Use1^tm1.2Aha Tg(Pcp2-cre)2Mpin/0 involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6 * SJL	abnormal gait	J:147771
	ataxia	J:147771
	decreased Purkinje cell number	J:147771
Use1^tm1.2Aha/Use1^tm1.2Aha involves: BALB/cJ * C57BL/6 * SJL	embryonic lethality, complete penetrance	J:147771
Use1^tm1Aha/Use1^tm1Aha Not Specified	embryonic lethality, complete penetrance	J:147771

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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