Cisd2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Cisd2
CDGSH iron sulfur domain 2
MGI:1914256

29 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Cisd2^{Gt(XS0445)Wtsi}/Cisd2^{Gt(XS0445)Wtsi} B6.129P2-Cisd2^{Gt(XS0445)Wtsi}	abnormal calcium ion homeostasis	J:183788
	abnormal mitochondrial crista morphology	J:183788
	abnormal mitochondrial shape	J:183788
	abnormal sarcomere morphology	J:183788
	abnormal skeletal muscle fiber morphology	J:183788
	abnormal skeletal muscle fiber type ratio	J:183788
	abnormal skeletal muscle morphology	J:183788
	decreased body weight	J:183788
	dilated sarcoplasmic reticulum	J:183788
	enhanced autophagy	J:183788
	impaired skeletal muscle contractility	J:183788
	increased mitochondrial size	J:183788
	lethargy	J:183788
	normal muscle phenotype	J:183788
	ruffled hair	J:183788
	tremors	J:183788
	weakness	J:183788
Cisd2^{tm1a(EUCOMM)Wtsi}/Cisd2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Cisd2^{tm1a(EUCOMM)Wtsi}/H	abnormal behavior	J:165965
	abnormal bone mineralization	J:165965
	abnormal eye size	J:165965
	abnormal glucose homeostasis	J:165965
	decreased body weight	J:165965
	decreased bone mineral density	J:165965
	decreased circulating amylase level	J:165965
	decreased circulating triglyceride level	J:165965
	decreased heart weight	J:165965
	decreased lean body mass	J:165965
	decreased locomotor activity	J:165965
	increased circulating aspartate transaminase level	J:165965
	increased circulating phosphate level	J:165965

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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