Aqp11 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aqp11
aquaporin 11
MGI:1913583

29 phenotypes from 4 alleles in 7 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aqp11^sjds/Aqp11^sjds involves: BALB/cRl	abnormal kidney cortex morphology	J:169660
	abnormal proximal convoluted tubule morphology	J:169660
	abnormal renal tubule epithelium morphology	J:169660
	abnormal renal tubule morphology	J:169660
	decreased body weight	J:169660
	decreased urine osmolality	J:169660
	increased blood urea nitrogen level	J:169660
	increased circulating creatinine level	J:169660
	kidney failure	J:169660
	pale kidney	J:169660
	postnatal lethality, complete penetrance	J:169660
	proximal convoluted tubule brush border loss	J:169660
Aqp11^sjds/Aqp11^sjds involves: BALB/cRl * C3H/Rl * C57BL/10Rl	postnatal lethality, complete penetrance	J:54592
Aqp11^sjds/Aqp11^tm1Lex involves: 129S5/SvEvBrd * BALB/cRl * C57BL/6 * CD-1	abnormal kidney cortex morphology	J:169660
	abnormal renal tubule morphology	J:169660
	increased blood urea nitrogen level	J:169660
	pale kidney	J:169660
	postnatal lethality, complete penetrance	J:169660
Aqp11^{tm1.1(KOMP)Vlcg}/Aqp11⁺ B6N(Cg)-Aqp11^{tm1.1(KOMP)Vlcg}/J	decreased leukocyte cell number	J:211773
	decreased urine magnesium level	J:211773
	fused cornea and lens	J:211773
Aqp11^tm1.1Nlsn/Aqp11^tm1.1Nlsn Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: 129S1/Sv * C57BL/6 * DBA	abnormal endoplasmic reticulum morphology	J:194939
	abnormal hepatocyte morphology	J:194939
	decreased blood urea nitrogen level	J:194939
	decreased circulating free fatty acids level	J:194939
	decreased circulating glycerol level	J:194939
	decreased circulating ketone body level	J:194939
	decreased circulating triglyceride level	J:194939
	normal homeostasis/metabolism phenotype	J:194939
	increased circulating aspartate transaminase level	J:194939
	increased circulating HDL cholesterol level	J:194939
Aqp11^tm1Lex/Aqp11^tm1Lex 129S5/SvEvBrd-Aqp11^tm1Lex	abnormal proximal convoluted tubule morphology	J:100522
	enlarged kidney	J:100522
	increased blood urea nitrogen level	J:100522
	kidney cortex cyst	J:100522
	kidney failure	J:100522
	pale kidney	J:100522
	postnatal growth retardation	J:100522
	premature death	J:100522
Aqp11^tm1Lex/Aqp11^tm1Lex involves: 129S5/SvEvBrd * C57BL/6 * CD-1	abnormal kidney cortex morphology	J:169660
	abnormal renal tubule morphology	J:169660
	decreased body weight	J:169660
	decreased urine osmolality	J:169660
	increased blood urea nitrogen level	J:169660
	kidney failure	J:169660
	premature death	J:169660

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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