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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Tnfrsf13b
tumor necrosis factor receptor superfamily, member 13b
MGI:1889411
38 phenotypes from 3 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Tnfrsf13btm1Cmac/Tnfrsf13btm1Cmac
Not Specified
enlarged spleen J:91914
normal immune system phenotype J:92334
increased B cell number J:91914
Tnfrsf13btm1Rjb/Tnfrsf13btm1Rjb
involves: 129X1/SvJ
abnormal class switch recombination J:95288
decreased IgA level J:95288
decreased IgE level J:95288
decreased IgG1 level J:95288
Tnfrsf13btm1Rjb/Tnfrsf13btm1Rjb
involves: 129X1/SvJ * C57BL/6
abnormal B cell activation J:69474
decreased IgA level J:69474
decreased IgM level J:69474
increased B cell number J:69474
increased B cell proliferation J:69474
increased spleen weight J:69474
Tnfrsf13btm1Vmd/Tnfrsf13btm1Vmd
involves: C57BL/6
abnormal immunoglobulin level J:70172
abnormal lymph node primary follicle morphology J:70172, J:82331
abnormal Peyer's patch follicle morphology J:70172
abnormal spleen morphology J:70172
abnormal spleen periarteriolar lymphoid sheath morphology J:70172, J:82331
abnormal spleen primary B follicle morphology J:70172
enlarged lymph nodes J:70172, J:82331
enlarged spleen J:70172, J:82331
glomerular crescent J:82331
glomerulonephritis J:82331
glomerulosclerosis J:82331
increased anti-double stranded DNA antibody level J:82331
increased anti-nuclear antigen antibody level J:82331
increased B cell number J:70172, J:82331
increased B cell proliferation J:70172
increased follicular B cell number J:70172
increased IgG1 level J:70172
increased leukemia incidence J:82331
increased marginal zone B cell number J:70172
increased mature B cell number J:70172
increased mesangial cell number J:82331
increased spleen germinal center size J:70172
increased spleen white pulp amount J:70172
increased transitional stage B cell number J:70172
increased urine protein level J:82331
kidney inflammation J:82331
liver inflammation J:82331
premature death J:82331
renal glomerular immunoglobulin deposits J:82331
renal glomerulus fibrosis J:82331

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory