27 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Dvl3tm1Awb/Dvl3+ Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat involves: 129 * C57BL/6	abnormal heart morphology	J:189062
	ventricular septal defect	J:189062
Fzd1tm1.1Nat/Fzd1+ Fzd2tm1.1Nat/Fzd2+ Vangl2Lp/Vangl2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * LPT/LeJ	open neural tube	J:165556
	ventricular septal defect	J:165556
Fzd1tm1.1Nat/Fzd1+ Fzd2tm1.1Nat/Fzd2tm1.1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal heart morphology	J:165556
Fzd1tm1.1Nat/Fzd1tm1.1Nat Fzd2tm1.1Nat/Fzd2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal heart morphology	J:165556
	cleft palate	J:165556
Fzd1tm1.1Nat/Fzd1tm1.1Nat Fzd2tm1.1Nat/Fzd2tm1.1Nat involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	abnormal cochlear hair cell morphology	J:165556
	abnormal cochlear hair cell number	J:165556
	abnormal heart morphology	J:165556
	abnormal mouth morphology	J:165556
	abnormal orientation of outer hair cell stereociliary bundles	J:165556
	abnormal palate development	J:165556
	cleft palate	J:165556
	cyanosis	J:165556
	double outlet right ventricle	J:165556
	normal embryo phenotype	J:165556
	failure of palatal shelf elevation	J:165556
	overriding aortic valve	J:165556
	palatal shelves fail to meet at midline	J:165556
	short mandible	J:165556
	ventricular septal defect	J:165556
Fzd2tm1.1Nat/Fzd2+ Vangl2Lp/Vangl2+ involves: 129 * C57BL/6 * LPT/LeJ	abnormal heart morphology	J:189062
	ventricular septal defect	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat involves: 129 * C57BL/6	abnormal heart morphology	J:189062
	normal craniofacial phenotype	J:189062
	double outlet right ventricle	J:189062
	postnatal lethality, incomplete penetrance	J:189062
	ventricular septal defect	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat involves: 129 * C57BL/6 * LPT/LeJ	cleft palate	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat Vangl2Lp/Vangl2+ involves: 129 * C57BL/6 * LPT/LeJ	abnormal heart morphology	J:189062
	cleft palate	J:189062
	ventricular septal defect	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat Wnt3atm1Amc/Wnt3a+ involves: 129 * C57BL/6	abnormal heart morphology	J:189062
	cleft palate	J:189062
	ventricular septal defect	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat Wnt5atm1Amc/Wnt5a+ involves: 129 * C57BL/6	embryonic growth retardation	J:189062
	embryonic lethality during organogenesis, complete penetrance	J:189062
Fzd2tm1.1Nat/Fzd2+ Fzd7tm1.1Nat/Fzd7tm1.1Nat Wnt11tm1Amc/Wnt11+ involves: 129 * C57BL/6	abnormal heart morphology	J:189062
	cleft palate	J:189062
	ventricular septal defect	J:189062
Fzd2tm1.1Nat/Fzd2tm1.1Nat Fzd7tm1.1Nat/Fzd7tm1.1Nat involves: 129 * C57BL/6	abnormal embryonic tissue morphology	J:189062
	abnormal heart development	J:189062
	abnormal parietal yolk sac morphology	J:189062
	decreased angiogenesis	J:189062
	decreased embryo size	J:189062
	disorganized yolk sac vascular plexus	J:189062
	embryonic growth retardation	J:189062
	embryonic lethality during organogenesis, complete penetrance	J:189062
	incomplete embryo turning	J:189062
	open neural tube	J:189062
Fzd2tm1.1Nat/Fzd2tm1.1Nat Vangl2Lp/Vangl2+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA * LPT/LeJ	abnormal cochlear hair cell morphology	J:165556
	abnormal cochlear hair cell number	J:165556
	abnormal orientation of outer hair cell stereociliary bundles	J:165556
	cleft palate	J:165556
	open neural tube	J:165556
	ventricular septal defect	J:165556