Aldh1a3 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aldh1a3
aldehyde dehydrogenase family 1, subfamily A3
MGI:1861722

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Aldh1a1^tm1.1Ngb/Aldh1a1^tm1.1Ngb Aldh1a3^tm1.1Pcn/Aldh1a3^tm1.1Pcn involves: 129/Sv * C57BL/6 * SJL	abnormal conjunctival sac morphology	J:102847
	abnormal corneal stroma development	J:102847
	abnormal eyelid development	J:102847
	abnormal nose morphology	J:102847
	absent Harderian gland	J:102847
	absent iris stroma	J:102847
	absent sclera	J:102847
	decreased periocular mesenchyme apoptosis	J:102847
	decreased ventral retina size	J:102847
	neonatal lethality, complete penetrance	J:102847
	persistent hyperplastic primary vitreous	J:102847
	respiratory distress	J:102847
	ventral rotation of lens	J:102847
Aldh1a1^tm1Gdu/Aldh1a1^tm1Gdu Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal optic cup morphology	J:108515
Aldh1a1^tm1Gdu/Aldh1a1^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal periocular mesenchyme morphology	J:108515
	abnormal posterior eye segment morphology	J:108515
	abnormal vitreous body morphology	J:108515
	decreased periocular mesenchyme apoptosis	J:108515
	increased corneal stroma thickness	J:108515
	increased total retina thickness	J:108515
	persistent hyperplastic primary vitreous	J:108515
	thick eyelids	J:108515
Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal optic cup morphology	J:108515
Aldh1a2^tm1Gdu/Aldh1a2^tm1Gdu Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * Swiss Webster	impaired branching involved in ureteric bud morphogenesis	J:157254
	renal hypoplasia	J:157254
Aldh1a3^tm1Gdu/Aldh1a3⁺ Chd7^{Gt(S20-7E1)Sor}/Chd7⁺ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662
Aldh1a3^tm1Gdu/Aldh1a3^tm1Gdu Chd7^{Gt(S20-7E1)Sor}/Chd7⁺ involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6J	abnormal semicircular canal morphology	J:314662

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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