Pqbp1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pqbp1
polyglutamine binding protein 1
MGI:1859638

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pqbp1^em1(IMPC)Tcp/Y C57BL/6N-Pqbp1^em1(IMPC)Tcp/Tcp	abnormal embryo size	J:211773
Pqbp1^tm1.1Hiok/Pqbp1⁺ Tg(Syn1-cre)671Jxm/0 involves: C57BL/6 * C57BL/6J	normal nervous system phenotype	J:279053
Pqbp1^tm1.1Hiok/Pqbp1⁺ Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J	decreased brain size	J:279053
Pqbp1^tm1.1Hiok/Y Tg(Nes-cre)1Kln/0 involves: C57BL/6 * C57BL/6J	abnormal cell cycle	J:279053
	abnormal cell cycle checkpoint function	J:279053
	abnormal dentate gyrus morphology	J:279053
	abnormal hippocampus CA1 region morphology	J:279053
	abnormal hippocampus pyramidal cell layer	J:279053
	abnormal mitosis	J:279053
	abnormal neuronal stem cell morphology	J:279053
	decreased brain size	J:279053
	decreased brain weight	J:279053
	impaired balance	J:279053
	impaired cued conditioning behavior	J:279053
	microcephaly	J:279053
	normal nervous system phenotype	J:279053
	thin cerebral cortex	J:279053
Pqbp1^tm1.1Hiok/Y Tg(Syn1-cre)671Jxm/0 involves: C57BL/6 * C57BL/6J	abnormal neuron morphology	J:279053
	normal nervous system phenotype	J:279053
Tg(CMV-RNAi:Pqbp1)1Hiok/0 involves: C57BL/6 * C57BL/6J	abnormal response to novel object	J:154081
	normal behavior/neurological phenotype	J:154081
	decreased anxiety-related response	J:154081

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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