48 phenotypes from 7 alleles in 10 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Prkntm1Ccs/Prkntm1Ccs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal dopamine level	J:127250
	abnormal neuron morphology	J:127707
	abnormal spatial learning	J:127250
	normal behavior/neurological phenotype	J:127250
	brain vacuoles	J:127707
	decreased exploration in new environment	J:127250
	impaired behavioral response to xenobiotic	J:127250
	increased anxiety-related response	J:127250
	increased thigmotaxis	J:127250
	normal nervous system phenotype	J:127250, J:127707
Prkntm1Ccs/Prkntm1Ccs involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal CNS glial cell morphology	J:168847
	abnormal mitochondrial morphology	J:168847
Prkntm1Roo/Prkntm1Roo either: 129S2/SvPas or (involves: 129S2/SvPas * C57BL/6)	abnormal stationary movement	J:85561
	abnormal synaptic transmission	J:85561
	decreased body weight	J:85561
	decreased core body temperature	J:85561
	decreased exploration in new environment	J:85561
	increased dopamine level	J:85561
	normal muscle phenotype	J:85561
	normal nervous system phenotype	J:85561
Prkntm1Roo/Prkntm1Roo involves: 129S2/SvPas	abnormal locomotor activation	J:125148
	abnormal posture	J:125148
	abnormal respiratory function	J:125148
	abnormal tail movements	J:125148
	alopecia	J:125148
	decreased substantia nigra size	J:125148
	hippocampal neuron degeneration	J:125148
	increased neuron apoptosis	J:125148
	kyphosis	J:125148
	loss of dopaminergic neurons	J:125148
	neuron degeneration	J:125148
	premature death	J:125148
	short stride length	J:125148
	tau protein deposits	J:125148
Prkntm1Rpa/Prkntm1Rpa involves: 129S4/SvJaeSor * C57BL/6	normal behavior/neurological phenotype	J:95204
	normal homeostasis/metabolism phenotype	J:95204
	normal nervous system phenotype	J:95204
Prkntm1Shn/Prkntm1Shn B6.129S4-Prkntm1Shn/J	abnormal autophagy	J:193741
	abnormal mitochondrial morphology	J:193741
	abnormal mitochondrial physiology	J:193741
	abnormal mitophagy	J:193741
	abnormal response to cardiac infarction	J:193741
	decreased body size	J:193741
	decreased mitochondrial size	J:193741
	impaired coordination	J:202221
	increased sensitivity to induced cell death	J:193741, J:194987
	increased susceptibility to induced morbidity/mortality	J:193741
Prkntm1Shn/Prkntm1Shn involves: 129S4/SvJae	abnormal nervous system electrophysiology	J:86377
	impaired coordination	J:86377
	increased dopamine level	J:86377
Prkntm1Tmd/Prkntm1Tmd involves: C57BL/6	abnormal locus ceruleus morphology	J:91487
	decreased noradrenaline level	J:91487
	decreased startle reflex	J:91487
Prkntm1Ykt/Prkntm1Ykt involves: 129P2/OlaHsd * C57BL/6	abnormal substantia nigra pars compacta morphology	J:117737
	decreased body weight	J:117737
	increased dopamine level	J:117737
Prkntm2Tmd/Prkntm2Tmd Not Specified	decreased dopaminergic neuron number	J:171058