Mapk8ip3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
MGI:1353598

43 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapk8ip3^tm1.1Ysok/Mapk8ip3^tm1.1Ysok involves: 129P2/OlaHsd * C57BL/6J	abnormal dorsal telencephalic commissure morphology	J:141459
	neonatal lethality, complete penetrance	J:141459
Mapk8ip3^tm1Plhn/Mapk8ip3^tm1Plhn involves: 129S4/SvJae * C57BL/6	abnormal lung development	J:136735
	abnormal lung saccule morphology	J:136735
	abnormal lung vasculature morphology	J:136735
	cyanosis	J:136735
	neonatal lethality, complete penetrance	J:136735
	respiratory failure	J:136735
Mapk8ip3^tm1Plhn/Mapk8ip3^tm1Plhn involves: 129S4/SvJae * C57BL/6J	abnormal anterior commissure morphology	J:95744
	abnormal anterior commissure pars anterior morphology	J:95744
	abnormal anterior commissure pars posterior morphology	J:95744
	abnormal axon guidance	J:95744
	abnormal cerebral cortex morphology	J:95744
	abnormal cerebral cortex pyramidal cell morphology	J:95744
	abnormal CNS glial cell morphology	J:95744
	abnormal corpus callosum morphology	J:95744
	abnormal cortical marginal zone morphology	J:95744
	abnormal diencephalon morphology	J:95744
	abnormal frontal lobe morphology	J:95744
	abnormal hippocampal fimbria morphology	J:95744
	abnormal hippocampus morphology	J:95744
	abnormal neuronal migration	J:95744
	abnormal optic tract morphology	J:95744
	abnormal parietal lobe morphology	J:95744
	abnormal subplate morphology	J:95744
	abnormal telencephalon development	J:95744
	abnormal telencephalon morphology	J:95744
	abnormal thalamus morphology	J:95744
	cyanosis	J:95744
	enlarged brain ventricles	J:95744
	increased hippocampal fornix size	J:95744
	increased optic chiasm size	J:95744
	neonatal lethality, complete penetrance	J:95744
	respiratory failure	J:95744
	thin cortical plate	J:95744
Mapk8ip3^tm1Rjd/Mapk8ip3^tm1Rjd B6.129S6-Mapk8ip3^tm1Rjd	abnormal axon guidance	J:85160
	abnormal brain commissure morphology	J:85160
	abnormal CNS synaptic transmission	J:85160
	abnormal pulmonary alveolus morphology	J:85160
	abnormal telencephalon development	J:85160
	anoxia	J:85160
	atelectasis	J:85160
	decreased brain size	J:85160
	dilated lateral ventricle	J:85160
	perinatal lethality, complete penetrance	J:85160
	respiratory failure	J:85160
	thick pulmonary interalveolar septum	J:85160
Mapk8ip3^tm1Ysok/Mapk8ip3^tm1Ysok involves: 129P2/OlaHsd * C57BL/6J	no abnormal phenotype detected	J:141459
Mapk8ip3^tm1Ysok/Mapk8ip3^tm1Ysok Tg(Nes-cre)1Kln/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL	abnormal dorsal telencephalic commissure morphology	J:141459
	neonatal lethality, incomplete penetrance	J:141459
	postnatal lethality, complete penetrance	J:141459

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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