Ofd1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ofd1
OFD1, centriole and centriolar satellite protein
MGI:1350328

41 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ofd1^tm1Bfra/Ofd1^tm1Bfra involves: 129S2/SvPas	abnormal limb mesenchyme morphology	J:168038
Ofd1^tm1Bfra/Ofd1^tm1Bfra involves: 129S2/SvPas	short radius	J:168038
Ofd1^tm2.1Bfra/Ofd1⁺ Tg(Prrx1-cre)1Cjt/0 involves: 129S2/SvPas * C57BL/6J * SJL/J	abnormal humerus morphology	J:168038
	abnormal limb development	J:168038
	abnormal limb mesenchyme morphology	J:168038
	preaxial polydactyly	J:168038
	short femur	J:168038
	short fibula	J:168038
	short humerus	J:168038
	short radius	J:168038
	short tibia	J:168038
	short ulna	J:168038
Ofd1^tm2.1Bfra/Ofd1⁺ Tg(CAG-cre)1Nagy/0 involves: 129S2/SvPas	abnormal blood vessel morphology	J:106035
	abnormal brain morphology	J:106035
	abnormal renal glomerulus morphology	J:106035
	abnormal rib morphology	J:106035
	abnormal sternum morphology	J:106035
	cleft palate	J:106035
	decreased cranium height	J:106035
	decreased embryo size	J:106035
	normal embryo phenotype	J:106035
	neonatal lethality, complete penetrance	J:106035
	polydactyly	J:106035
	renal glomerulus cyst	J:106035
	short limbs	J:106035
	small lung	J:106035
	syndactyly	J:106035
Ofd1^tm2.1Bfra/Y Tg(CAG-cre)1Nagy/0 involves: 129S2/SvPas	abnormal direction of heart looping	J:106035
	abnormal heart tube morphology	J:106035
	abnormal left-right axis patterning	J:106035
	abnormal neuron differentiation	J:106035
	absent floor plate	J:106035
	decreased embryo size	J:106035
	distended pericardium	J:106035
	embryonic lethality during organogenesis, incomplete penetrance	J:106035
	incomplete embryo turning	J:106035
Ofd1^tm2.1Bfra/Y Tg(Msx2-cre)5Rem/0 involves: 129S2/SvPas	normal limbs/digits/tail phenotype	J:168038
Ofd1^tm2.1Bfra/Y Tg(Prrx1-cre)1Cjt/0 involves: 129S2/SvPas * C57BL/6J * SJL/J	abnormal bone mineralization	J:168038
	abnormal chondrocyte physiology	J:168038
	abnormal humerus morphology	J:168038
	abnormal limb mesenchyme morphology	J:168038
	abnormal long bone diaphysis morphology	J:168038
	abnormal long bone epiphyseal plate morphology	J:168038
	decreased length of long bones	J:168038
	decreased long bone epiphyseal plate size	J:168038
	polydactyly	J:168038
	postnatal lethality	J:168038
	short femur	J:168038
	short fibula	J:168038
	short humerus	J:168038
	short radius	J:168038
	short tibia	J:168038
	short ulna	J:168038
	syndactyly	J:168038

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