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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Foxg1
forkhead box G1
MGI:1347464
59 phenotypes from 4 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Foxg1em1Skyl/Foxg1+
C57BL/6J-Foxg1em1Skyl 		abnormal brain interneuron morphology J:367353
abnormal cortical ventricular zone morphology J:367353
abnormal dentate gyrus morphology J:367353
abnormal innervation J:367353
abnormal myelination J:367353
abnormal neuron differentiation J:367353
abnormal oligodendrocyte differentiation J:367353
absent corpus callosum J:367353
behavioral arrest J:367353
decreased brain size J:367353
decreased brain weight J:367353
decreased corpus callosum size J:367353
decreased locomotor activity J:367353
impaired coordination J:367353
increased grooming behavior J:367353
increased oligodendrocyte progenitor number J:367353
increased radial glial cell number J:367353
increased thigmotaxis J:367353
small hippocampus J:367353
stereotypic behavior J:367353
thin cerebral cortex J:367353
Foxg1em1Skyl/Foxg1em1Skyl
C57BL/6J-Foxg1em1Skyl 		abnormal craniofacial morphology J:367353
abnormal eye development J:367353
abnormal forebrain morphology J:367353
abnormal frontonasal prominence morphology J:367353
neonatal lethality, complete penetrance J:367353
Foxg1tm1(cre)Skm/Foxg1+
129(Cg)-Foxg1tm1(cre)Skm/J 		no abnormal phenotype detected J:62916
Foxg1tm1(cre)Skm/Foxg1+
B6.129P2-Foxg1tm1(cre)Skm 		abnormal cerebral cortex morphology J:128207
abnormal cerebral hemisphere morphology J:128207
abnormal telencephalon morphology J:128207
decreased cerebral cortex pyramidal cell number J:128207
decreased forebrain volume J:128207
decreased hippocampus volume J:128207
decreased striatum size J:128207
small thalamus J:128207
thin cerebral cortex J:128207
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * C57BL/6J 		abnormal cerebral cortex pyramidal cell morphology J:235875
abnormal visual cortex morphology J:235875
abnormal visual evoked potential J:235875
decreased visual acuity J:235875
Foxg1tm1(cre)Skm/Foxg1+
involves: C57BL/6 * CBA 		abnormal brain morphology J:128207
Foxg1tm1(cre)Skm/Foxg1tm1(cre)Skm
129(Cg)-Foxg1tm1(cre)Skm/J 		perinatal lethality, complete penetrance J:62916
Foxg1tm1Chzh/Foxg1tm1Chzh
Tg(Fzd9-cre/ERT)1Chzh/0
involves: C57BL/6 * FVB 		abnormal dentate gyrus morphology J:182692
abnormal neuronal precursor proliferation J:182692
abnormal radial glial cell morphology J:182692
Foxg1tm1M/Foxg1+
involves: C57BL/6 * CBA 		abnormal brain morphology J:128207
Foxg1tm1M/Foxg1tm1M
involves: 129S1/Sv 		abnormal neocortex morphology J:78115
abnormal neural tube mantle layer morphology J:78115
abnormal neuron differentiation J:78115
abnormal neuronal precursor proliferation J:78115
abnormal telencephalon morphology J:78115
Foxg1tm1M/Foxg1tm1M
involves: 129S1/Sv * C57BL/6J 		abnormal cerebral cortex morphology J:26720
abnormal cerebral hemisphere morphology J:26720
abnormal cranium morphology J:26720
abnormal embryonic/fetal subventricular zone morphology J:26720
abnormal eye morphology J:26720
abnormal nasal placode morphology J:26720
abnormal olfactory epithelium morphology J:26720
abnormal retina morphology J:26720
abnormal retina neuronal layer morphology J:26720
abnormal telencephalon development J:26720
abnormal telencephalon morphology J:26720
cyanosis J:26720
neonatal lethality, complete penetrance J:26720
no spontaneous movement J:26720
respiratory distress J:26720
respiratory failure J:26720
small embryonic telencephalon J:26720
small olfactory bulb J:26720
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory