89 phenotypes from 13 alleles in 16 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mapk14tm1.1Dvb/Mapk14+ B6(FVB)-Mapk14tm1.1Dvb	decreased circulating glucose level	J:151980
	decreased pancreatic beta cell proliferation	J:151980
	increased pancreatic beta cell proliferation	J:151980
Mapk14tm1.1Dvb/Mapk14tm1.1Dvb B6(FVB)-Mapk14tm1.1Dvb	embryonic lethality during organogenesis	J:151980
Mapk14tm1.1Lex/Mapk14tm1.1Lex involves: 129S4/SvJaeSor * 129S5/SvEvBrd * C57BL/6J	abnormal muscle fiber morphology	J:119724
	abnormal myoblast differentiation	J:119724
	abnormal myoblast fusion	J:119724
	increased myoblast proliferation	J:119724
Mapk14tm1.1Otsu/Mapk14tm1.1Otsu involves: C57BL/6J	embryonic lethality during organogenesis, complete penetrance	J:95116
Mapk14tm1.1Otsu/Mapk14tm1.2Otsu Slc6a3tm1(cre)Xz/0 involves: 129S1/Sv * C57BL/6	abnormal associative learning	J:226396
	normal behavior/neurological phenotype	J:226396
Mapk14tm1.2Otsu/Mapk14tm1.2Otsu involves: C57BL/6J	no abnormal phenotype detected	J:95116
Mapk14tm1.2Otsu/Mapk14tm1.2Otsu Tg(Col2a1-cre)1Bhr/0 involves: C57BL/6 * SJL	abnormal long bone epiphyseal plate proliferative zone	J:204227
	decreased body length	J:204227
	decreased body size	J:204227
	decreased long bone epiphyseal plate size	J:204227
	decreased width of hypertrophic chondrocyte zone	J:204227
	normal homeostasis/metabolism phenotype	J:204227
	kyphosis	J:204227
	short femur	J:204227
	short tibia	J:204227
	small vertebrae	J:204227
Mapk14tm1.2Otsu/Mapk14tm1.2Otsu Tg(Myh6-cre)2182Mds/0 involves: C57BL/6J	cardiac fibrosis	J:95116
	decreased cardiac muscle contractility	J:95116
	enlarged heart	J:95116
	increased cardiomyocyte apoptosis	J:95116
	increased heart weight	J:95116
	increased response of heart to induced stress	J:95116
	increased susceptibility to induced morbidity/mortality	J:95116
Mapk14tm1Gab/Mapk14tm1Gab involves: DBA/1LacJ	embryonic lethality during organogenesis, complete penetrance	J:60918
Mapk14tm1Jda/Mapk14tm1Jda B6.Cg-Mapk14tm1Jda	abnormal T-helper 1 physiology	J:146088
	decreased interferon-alpha secretion	J:146088
	decreased interferon-gamma secretion	J:146088
	decreased T cell proliferation	J:146088
	increased double-negative T cell number	J:146088
Mapk14tm1Lex/Mapk14tm1Lex Myl7tm1(cre)Krc/Myl7+ involves: 129S1/Sv * 129S5/SvEvBrd * 129X1/SvJ * C57BL/6	abnormal fetal cardiomyocyte proliferation	J:98514
Mapk14tm1Lex/Mapk14tm1Lex Tg(Myog-cre)1Eno/0 involves: 129S5/SvEvBrd	normal cardiovascular system phenotype	J:155408
	normal cellular phenotype	J:155408
	normal muscle phenotype	J:155408
Mapk14tm1Mka/Mapk14+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal response to cardiac infarction	J:82448
	decreased myocardial infarct size	J:82448
Mapk14tm1Mka/Mapk14tm1Mka involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal erythropoiesis	J:63425
	abnormal placental labyrinth vasculature morphology	J:63425
	anemia	J:63425
	embryonic growth retardation	J:63425
	embryonic lethality during organogenesis, incomplete penetrance	J:63425
	lethality throughout fetal growth and development, complete penetrance	J:63425
	pale liver	J:63425
	pale yolk sac	J:63425
	pallor	J:63425
	small liver	J:63425
Mapk14tm1Mms/Mapk14tm1Mms involves: 129S7/SvEvBrd * C57BL/6	abnormal angiogenesis	J:73417
	abnormal cell physiology	J:73417
	abnormal placenta morphology	J:73417
	abnormal placental labyrinth vasculature morphology	J:73417
	abnormal vitelline vascular remodeling	J:73417
	absent placental labyrinth	J:73417
	decreased spongiotrophoblast size	J:73417
	decreased trophoblast giant cell number	J:73417
	embryonic growth retardation	J:73417
	embryonic lethality during organogenesis, complete penetrance	J:73417
	normal hematopoietic system phenotype	J:73417
Mapk14tm1Nbr/Mapk14tm1Nbr either: (involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6) or (involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1)	abnormal cranial blood vasculature morphology	J:63877
	abnormal placenta development	J:63877
	abnormal placenta labyrinth morphology	J:63877
	abnormal placenta vasculature	J:63877
	abnormal placental labyrinth vasculature morphology	J:63877
	abnormal trophoblast layer morphology	J:63877
	absent myocardial trabeculae	J:63877
	decreased cardiac muscle contractility	J:63877
	decreased fetal cardiomyocyte number	J:63877
	embryonic growth retardation	J:63877
	embryonic lethality during organogenesis, complete penetrance	J:63877
	impaired placental function	J:63877
	increased embryonic tissue cell apoptosis	J:63877
	pale yolk sac	J:63877
	pallor	J:63877
	poor circulation	J:63877
	thin myocardium	J:63877
Mapk14tm1Nbr/Mapk14tm2Nbr Polr2atm1(cre/ERT2)Bbd/Polr2a+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1 * SJL	abnormal lung development	J:122397
	abnormal tumor incidence	J:122397
	enlarged lung	J:122397
	increased lung adenocarcinoma incidence	J:122397
	increased lung adenoma incidence	J:122397
	increased lung tumor incidence	J:122397
	premature death	J:122397
Mapk14tm1Okee/Mapk14tm1Okee involves: 129S6/SvEvTac * C57BL/6	decreased physiological sensitivity to xenobiotic	J:128965
Mapk14tm2Nbr/Mapk14tm2Nbr Polr2atm1(cre/ERT2)Bbd/Polr2a+ involves: 129 * C57BL/6 * CD-1 * SJL	abnormal cell cycle	J:122397
	abnormal lung epithelium morphology	J:122397
	abnormal lung morphology	J:122397
	abnormal pulmonary alveolus epithelial cell morphology	J:122397
	increased cell proliferation	J:122397
Tg(Myh6-Mapk14*)1Jmol/0 FVB-Tg(Myh6-Mapk14*)1Jmol	abnormal heart left ventricle morphology	J:83547
	cardiac hypertrophy	J:83547
	cardiac interstitial fibrosis	J:83547
	cardiomyopathy	J:83547
	decreased cardiac muscle contractility	J:83547
	decreased ventricle muscle contractility	J:83547
	heart left ventricle hypertrophy	J:83547
	increased myocardial fiber size	J:83547
	premature death	J:83547