Klf4 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Klf4
Kruppel-like transcription factor 4 (gut)
MGI:1342287

9 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
\Atg5^tm1.1Myok/\Atg5^tm1.1Myok \Col1a1^{tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae}/\Col1a1⁺ involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N	abnormal cell physiology	J:205532
\Col1a1^{tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae}/\Col1a1^{tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae} \Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/\Gt(ROSA)26Sor^{tm1(rtTAM2)Jae} involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:157298
\Klf4^tm1Khk/\Klf4⁺ \Krit1^tm1Kwhi/\Krit1^tm1Kwhi \Tg(Cdh5-cre/ERT2)1Rha/0 involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal brain vasculature morphology	J:232707
\Klf4^tm1Khk/\Klf4^tm1Khk \Klf5^tm1Jaw/\Klf5^tm1Jaw \Tg(Pax6-cre,GFP)1Pgr/0 involves: 129S6/SvEvTac * FVB	abnormal conjunctival epithelium morphology	J:175263
	abnormal cornea epithelium morphology	J:175263
	abnormal ocular surface morphology	J:175263
	absent conjunctiva goblet cells	J:175263
	decreased cornea stroma thickness	J:175263
	eyelids fail to open	J:175263

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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