Neurod1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Neurod1
neurogenic differentiation 1
MGI:1339708

45 phenotypes from 5 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Neurod1^m1Btlr/Neurod1^m1Btlr C57BL/6J-Neurod1^m1Btlr	head tossing	J:255210
Neurod1^m1Btlr/Neurod1^m1Btlr C57BL/6J-Neurod1^m1Btlr	hyperactivity	J:255210
Neurod1^tm1.1Kan/Neurod1^tm1.1Kan Tg(Gabra6-cre)B1Lfr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	normal nervous system phenotype	J:101098
Neurod1^tm1Jle/Neurod1^tm1Jle involves: 129S4/SvJaeSor * C57BL/6	abnormal amacrine cell morphology	J:51299
	abnormal Muller cell morphology	J:51299
	abnormal retina apoptosis	J:51299
	abnormal retina bipolar cell morphology	J:51299
	hyperglycemia	J:74715
	postnatal lethality, complete penetrance	J:74715
Neurod1^tm1Jle/Neurod1^tm1Jle involves: 129S4/SvJaeSor * ICR	increased retina apoptosis	J:121047
Neurod1^tm1Kan/Neurod1^tm1Kan involves: 129P2/OlaHsd	perinatal lethality, complete penetrance	J:101098
Neurod1^tm1Kan/Neurod1^tm1Mjts involves: 129P2/OlaHsd * 129S7/SvEvBrd	perinatal lethality, complete penetrance	J:101098
Neurod1^tm1Mjts/Neurod1^tm1Mjts involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6J	abnormal brain wave pattern	J:59932
	abnormal cerebellum morphology	J:59932
	abnormal dentate gyrus morphology	J:59932
	abnormal head movements	J:59932
	abnormal hippocampus CA4 region morphology	J:59932
	abnormal hippocampus development	J:59932
	abnormal hippocampus granule cell layer	J:59932
	abnormal hippocampus granule cell morphology	J:59932
	abnormal hippocampus morphology	J:59932
	ataxia	J:59932
	circling	J:59932
	normal homeostasis/metabolism phenotype	J:59932
	hyperactivity	J:59932
	hyperglycemia	J:59932
	postnatal lethality, incomplete penetrance	J:59932
	seizures	J:59932
	sporadic seizures	J:59932
	tonic-clonic seizures	J:59932
Neurod1^tm1Mjts/Neurod1^tm1Mjts involves: 129S7/SvEvBrd * C57BL/6	abnormal intestinal enteroendocrine cell morphology	J:43010
	abnormal intestinal mucosa morphology	J:43010
	abnormal pancreatic acinar cell morphology	J:43010
	abnormal pancreatic beta cell morphology	J:43010
	absent pancreatic islets	J:43010
	decreased body size	J:43010
	decreased pancreatic alpha cell number	J:43010
	decreased pancreatic beta cell number	J:43010
	decreased pancreatic delta cell number	J:43010
	dehydration	J:43010
	hyperglycemia	J:43010
	increased pancreas apoptosis	J:43010
	ketoaciduria	J:43010
	pancreatic acinar cell zymogen granule accumulation	J:43010
	postnatal lethality, complete penetrance	J:43010
Neurod1^tm1Mjts/Neurod1^tm1Mjts involves: 129X1/SvJ	abnormal lung epithelium morphology	J:137934
	decreased solitary pulmonary neuroendocrine cell number	J:137934
	impaired lung alveolus development	J:137934
	increased number of pulmonary neuroendocrine bodies	J:137934
	overexpanded pulmonary alveolus	J:137934

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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