78 phenotypes from 6 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Wt1tm1(EGFP/cre)Wtp/Wt1+ Zfpm2tm1Sho/Zfpm2tm2Sho involves: 129S1/Sv * 129S4/SvJae * 129S7/SvEvBrd	abnormal atrioventricular cushion morphology	J:150452
	normal cardiovascular system phenotype	J:150452
	perinatal lethality, complete penetrance	J:150452
	thin myocardium compact layer	J:150452
Zfpm2lil/Zfpm2lil involves: A/J	abnormal coronary vessel morphology	J:100119
	abnormal diaphragm morphology	J:100119
	abnormal right lung middle lobe morphology	J:100119
	absent right lung accessory lobe	J:100119
	complete atrioventricular septal defect	J:100119
	double outlet right ventricle	J:100119
	increased atrioventricular cushion size	J:100119
	increased heart atrium size	J:100119
	lethality throughout fetal growth and development, complete penetrance	J:100119
	ostium primum atrial septal defect	J:100119
	pulmonary hypoplasia	J:100119
	thin diaphragm muscle	J:100119
	thin myocardium	J:100119
	thin myocardium compact layer	J:100119
	ventricular septal defect	J:100119
Zfpm2lil/Zfpm2tm1Sho involves: 129S1/Sv * A/J	prenatal lethality, incomplete penetrance	J:100119
Zfpm2tm1.1Esv/Zfpm2+ involves: 129S1/SvImJ * 129S4/SvJae * 129S6/SvEvTac	no abnormal phenotype detected	J:216295
Zfpm2tm1.1Esv/Zfpm2tm1.1Esv involves: 129S1/SvImJ * 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6	abnormal heart echocardiography feature	J:216295
	atrial septal defect	J:216295
	decreased ventricle muscle contractility	J:216295
	thin myocardium compact layer	J:216295
	ventricular septal defect	J:216295
Zfpm2tm1Jml/Zfpm2tm1Jml involves: 129X1/SvJ	abnormal aortic valve morphology	J:63121
	abnormal heart atrium morphology	J:63121
	abnormal heart development	J:63121
	abnormal heart right ventricle morphology	J:63121
	abnormal heart valve morphology	J:63121
	abnormal heart ventricle morphology	J:63121
	abnormal heart ventricle outflow tract morphology	J:63121
	abnormal pulmonary valve morphology	J:63121
	common atrioventricular valve	J:63121
	complete atrioventricular septal defect	J:63121
	congestive heart failure	J:63121
	dilated heart atrium	J:63121
	embryonic lethality during organogenesis, complete penetrance	J:63121
	heart right ventricle outflow tract stenosis	J:63121
	pericardial edema	J:63121
	pulmonary valve hyperplasia	J:63121
	skin edema	J:63121
	thick pulmonary valve	J:63121
	thin left ventricle myocardium compact layer	J:63121
	tricuspid valve atresia	J:63121
	ventricular septal defect	J:63121
Zfpm2tm1Sho/Zfpm2+ C57BL/6JEi-Chr YA/HeJ/EiJ	ovotestis	J:125196
	primary sex reversal	J:125196
	true hermaphroditism	J:125196
Zfpm2tm1Sho/Zfpm2tm1Sho involves: 129S1/Sv	abnormal cardiac epithelial to mesenchymal transition	J:62879
	abnormal heart atrium morphology	J:62879
	abnormal lung development	J:62879, J:100119
	absent coronary vessels	J:62879
	absent right lung accessory lobe	J:100119
	atrial septal defect	J:62879
	common atrioventricular valve	J:62879
	congestive heart failure	J:62879
	decreased heart rate	J:62879
	dilated heart atrium	J:62879
	globular heart	J:62879
	heart right ventricle outflow tract stenosis	J:62879
	hemorrhage	J:62879
	hydrops fetalis	J:62879
	lethality throughout fetal growth and development, complete penetrance	J:62879
	overriding aortic valve	J:62879
	pallor	J:62879
	pulmonary hypoplasia	J:62879, J:100119
	small liver	J:62879
	supravalvar pulmonary trunk stenosis	J:62879
	thin ventricle myocardium compact layer	J:62879
	thin ventricular wall	J:62879
	ventricular myocardium compact layer hypoplasia	J:62879
	ventricular septal defect	J:62879
Zfpm2tm1Sho/Zfpm2tm1Sho Tg(Myh6-Zfpm2)1Sho/0 involves: 129S1/Sv	abnormal Leydig cell differentiation	J:78688
	abnormal ovary morphology	J:78688
	abnormal primary sex determination	J:78688
	abnormal Sertoli cell morphology	J:78688
	normal cardiovascular system phenotype	J:62879
	common atrioventricular valve	J:62879
	lethality throughout fetal growth and development, complete penetrance	J:62879
	primary sex reversal	J:78688
Zfpm2tm1Sho/Zfpm2tm2Sho H2az2Tg(Wnt1-cre)11Rth/H2az2+ involves: 129S1/Sv * C57BL/6 * CBA	normal cardiovascular system phenotype	J:150452
	normal mortality/aging	J:150452
Zfpm2tm1Sho/Zfpm2tm2Sho Nkx2-5tm1(cre)Rjs/Nkx2-5+ involves: 129S1/Sv * 129S7/SvEvBrd	abnormal atrioventricular cushion morphology	J:150452
	abnormal coronary vessel morphology	J:150452
	atrial septal defect	J:150452
	hemorrhage	J:150452
	lethality throughout fetal growth and development, complete penetrance	J:150452
	overriding aortic valve	J:150452
	pericardial effusion	J:150452
	skin edema	J:150452
	thin myocardium compact layer	J:150452
	ventricular septal defect	J:150452
Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Myh6-cre)2182Mds/0 involves: 129S1/Sv * 129S7/SvEvBrd	abnormal cardiovascular development	J:150452
	abnormal coronary circulation	J:150452
	cardiac fibrosis	J:150452
	normal cardiovascular system phenotype	J:150452
	decreased cardiac muscle contractility	J:150452
	decreased ventricle muscle contractility	J:150452
	dilated heart	J:150452
	dilated heart ventricle	J:150452
	increased cardiomyocyte apoptosis	J:150452
	postnatal lethality, complete penetrance	J:150452
	premature death	J:150452
Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Tek-cre)1Ywa/0 involves: 129S1/Sv * C57BL/6 * SJL	normal cardiovascular system phenotype	J:150452
	normal mortality/aging	J:150452
Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Tnnt2-rtTA,tetO-cre)1Wtp/0 involves: 129S1/Sv * 129S7/SvEvBrd	abnormal cardiovascular development	J:150452
	decreased cardiac muscle contractility	J:150452
	increased cardiomyocyte apoptosis	J:150452
Zfpm2tm1Sho/Zfpm2tm2Sho Tg(Wap-cre)11738Mam/0 involves: 129 * C57BL/6J * C57BL/6NCr	abnormal involution of the mammary gland	J:120985
	abnormal mammary gland morphology	J:120985
	normal reproductive system phenotype	J:120985
Zfpm2tm2Sho/Zfpm2tm2Sho involves: 129 * C57BL/6J	no abnormal phenotype detected	J:120985
Zfpm2tm2Sho/Zfpm2tm2Sho involves: 129S1/Sv	abnormal myocardial fiber physiology	J:150452