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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Epn2
epsin 2
MGI:1333766
30 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Epn1tm1.1Wami/Epn1tm1.1Wami
Epn2tm1Ocr/Epn2tm1Ocr
Tg(Cdh5-cre)7Mlia/0
involves: C57BL/6J * FVB/N 		decreased tumor growth/size J:193966
Epn1tm1.1Wami/Epn1tm1.1Wami
Epn2tm1Ocr/Epn2tm1Ocr
Tg(Cdh5-cre/ERT2)CIVE23Mlia/0
involves: 129X1/SvJ * C57BL/6J 		abnormal tumor vascularization J:193966
abnormal vascular endothelial cell migration J:193966
abnormal vascular endothelial cell physiology J:193966
decreased incidence of tumors by chemical induction J:193966
decreased susceptibility to induced morbidity/mortality J:193966
decreased tumor growth/size J:193966
increased vascular endothelial cell proliferation J:193966
increased vascular permeability J:193966
Epn1tm1.1Wami/Epn1tm1.1Wami
Epn2tm1Ocr/Epn2tm1Ocr
Tg(Cdh5-cre/ERT2)CIVE23Mlia/0
Tg(TRAMP)8247Ng/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6J 		decreased tumor growth/size J:193966
increased tumor-free survival time J:193966
Epn1tm1Ocr/Epn1+
Epn2tm1Ocr/Epn2tm1Ocr
B6.129X1-Epn1tm1Ocr Epn2tm1Ocr 		decreased survivor rate J:151951
premature death J:151951
slow postnatal weight gain J:151951
Epn1tm1Ocr/Epn1tm1Ocr
Epn2tm1Ocr/Epn2+
B6.129X1-Epn1tm1Ocr Epn2tm1Ocr 		decreased survivor rate J:151951
premature death J:151951
reduced fertility J:151951
slow postnatal weight gain J:151951
Epn1tm1Ocr/Epn1tm1Ocr
Epn2tm1Ocr/Epn2tm1Ocr
B6.129X1-Epn1tm1Ocr Epn2tm1Ocr 		abnormal blood vessel morphology J:151951
abnormal brain vasculature morphology J:151951
abnormal developmental vascular remodeling J:151951
abnormal embryo turning J:151951
abnormal neural tube morphology J:151951
abnormal somite development J:151951
abnormal somite shape J:151951
abnormal somite size J:151951
abnormal vitelline vascular remodeling J:151951
absent placental labyrinth J:151951
normal cellular phenotype J:151951
decreased embryo size J:151951
embryonic growth arrest J:151951
embryonic lethality during organogenesis, complete penetrance J:151951
incomplete somite formation J:151951
open neural tube J:151951
thin ventricular wall J:151951
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory