46 phenotypes from 3 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ltbp4em1(IMPC)Tcp/Ltbp4em1(IMPC)Tcp C57BL/6NCrl-Ltbp4em1(IMPC)Tcp/Tcp	abnormal sternum morphology	J:211773
	enlarged spleen	J:211773
Ltbp4Gt(E301B04)Wrst/Ltbp4Gt(E301B04)Wrst B6N.129P2-Ltbp4Gt(E301B04)Wrst	abnormal aorta elastic fiber morphology	J:221200
	abnormal aorta morphology	J:221200
	abnormal cardiovascular system physiology	J:221200
	abnormal heart left ventricle morphology	J:221200
	abnormal interventricular septum morphology	J:221200
	abnormal lung morphology	J:221200
	abnormal pulmonary alveolar system morphology	J:221200
	abnormal pulmonary elastic fiber morphology	J:221200
	abnormal respiratory system physiology	J:221200
	abnormal skin morphology	J:221200
	atelectasis	J:221200
	decreased body size	J:221200
	decreased body weight	J:221200
	emphysema	J:221200
	enlarged heart	J:221200
	heart right ventricle hypertrophy	J:221200
	impaired skin barrier function	J:221200
	increased aorta wall thickness	J:221200
	increased heart right ventricle wall thickness	J:221200
	postnatal lethality, incomplete penetrance	J:221200
	rectal prolapse	J:221200
	respiratory distress	J:221200
	thin dermal layer	J:221200
Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel B6.129S2-Ltbp4Gt(U3Cre)1Vmel	abnormal cell physiology	J:78819
	abnormal colon morphology	J:78819
	abnormal intestinal goblet cell morphology	J:78819
	abnormal intestinal mucosa morphology	J:78819
	abnormal large intestine crypts of Lieberkuhn morphology	J:78819
	abnormal pulmonary alveolus morphology	J:78819
	abnormal pulmonary alveolus wall morphology	J:78819
	abnormal pulmonary elastic fiber morphology	J:78819
	atelectasis	J:78819
	colitis	J:78819
	dilated heart ventricle	J:78819
	emphysema	J:78819
	enlarged lung	J:78819
	enlarged spleen	J:78819
	increased heart weight	J:78819
	increased large intestine adenocarcinoma incidence	J:78819
	increased lung compliance	J:78819
	increased myocardial fiber size	J:78819
	intestinal ulcer	J:78819
	overexpanded pulmonary alveolus	J:78819
	proctitis	J:78819
	rectal prolapse	J:78819
	respiratory distress	J:78819
	ventricular cardiomyopathy	J:78819
Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel involves: 129S2/SvPas	abnormal aorta elastic fiber morphology	J:221200
	abnormal aorta morphology	J:221200
	abnormal heart left ventricle morphology	J:221200
	abnormal interventricular septum morphology	J:221200
	abnormal lung morphology	J:221200
	abnormal pulmonary alveolar system morphology	J:221200
	abnormal pulmonary elastic fiber morphology	J:160854, J:221200
	abnormal skin morphology	J:221200
	atelectasis	J:221200
	emphysema	J:160854
	enlarged heart	J:221200
	increased lung compliance	J:160854
	normal mortality/aging	J:221200
Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel involves: 129S2/SvPas * 129X1/SvJ	postnatal lethality, incomplete penetrance	J:78819
Ltbp4Gt(U3Cre)1Vmel/Ltbp4Gt(U3Cre)1Vmel involves: 129S2/SvPas * C57BL/6	cardiomyopathy	J:85162
	emphysema	J:85162
	increased gastrointestinal tumor incidence	J:85162