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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Slit2
slit guidance ligand 2
MGI:1315205
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Ext1tm1Yama/\Ext1+
\Slit2tm1Matl/\Slit2tm1Matl
\Tg(Nes-cre)1Kln/0
involves: 129S2/SvPas * 129S5/SvEvBrd * C57BL/6 * SJL 		abnormal axon guidance J:86465
\Gdnftm1Rosl/\Gdnf+
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129S2/SvPas 		abnormal ureter morphology J:90324
\Ntn1Gt(ST629)Byg/\Ntn1Gt(ST629)Byg
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129P2/OlaHsd * 129S2/SvPas 		abnormal cell adhesion J:106011
abnormal mammary gland duct morphology J:106011
\Robo3tm1Matl/\Robo3tm1Matl
\Slit1tm1.1Matl/\Slit1tm1.1Matl
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129/Sv * CD-1 		abnormal axon guidance J:89438
\Robo3tm1Matl/\Robo3tm1Matl
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129/Sv * CD-1 		abnormal axon guidance J:89438
\Slit1tm1.1Matl/\Slit1+
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129S2/SvPas 		abnormal olfactory tract morphology J:119469
\Slit1tm1.1Matl/\Slit1tm1.1Matl
\Slit2tm1Matl/\Slit2+
involves: 129S2/SvPas 		abnormal olfactory tract morphology J:119469
\Slit1tm1.1Matl/\Slit1tm1.1Matl
\Slit2tm1Matl/\Slit2tm1Matl
involves: 129S2/SvPas 		abnormal embryonic/fetal subventricular zone morphology J:130430
abnormal neurite morphology J:130430
abnormal olfactory lobe morphology J:119469
abnormal olfactory tract morphology J:119469
normal nervous system phenotype J:130430
perinatal lethality, complete penetrance J:130430
\Slit1tm1.1Matl/\Slit1tm1.1Matl
\Slit2tm1Matl/\Slit2tm1Matl
\Slit3tm1.1Dor/\Slit3+
involves: 129S1/Sv * 129S2/SvPas 		abnormal axon guidance J:89780
abnormal spinal cord lateral column morphology J:89780
abnormal spinal cord ventral commissure morphology J:89780
\Slit1tm1.1Matl/\Slit1tm1.1Matl
\Slit2tm1Matl/\Slit2tm1Matl
\Slit3tm1.1Dor/\Slit3tm1.1Dor
involves: 129S1/Sv * 129S2/SvPas 		abnormal axon guidance J:89780
abnormal spinal cord lateral column morphology J:89780
\Slit2tm1Matl/\Slit2tm1Matl
\Slit3tm1.1Dor/\Slit3tm1.1Dor
involves: 129S1/Sv * 129S2/SvPas 		abnormal mammary gland duct morphology J:141875
increased mammary gland epithelial cell proliferation J:141875
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory