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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
MGI:1309464
17 phenotypes from 5 alleles in 5 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mapk8ip1tm1Plhn/Mapk8ip1tm1Plhn
either: B6.129S4-Mapk8ip1tm1Plhn or (involves: 129S4/SvJae * C57BL/6J) 		decreased susceptibility to ischemic brain injury J:104842
Mapk8ip1tm1Rjd/Mapk8ip1tm1Rjd
involves: 129S6/SvEvTac * C57BL/6 		abnormal NMDA-mediated synaptic currents J:125318
decreased susceptibility to neuronal excitotoxicity J:77616
normal homeostasis/metabolism phenotype J:77616
Mapk8ip1tm1Wae/Mapk8ip1+
either: (involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6) 		normal homeostasis/metabolism phenotype J:70600
normal reproductive system phenotype J:70600
Mapk8ip1tm1Wae/Mapk8ip1tm1Wae
either: (involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6) or (involves: 129P2/OlaHsd * C57BL/6) 		abnormal cell death J:70600
embryonic lethality before implantation, complete penetrance J:70600
Mapk8ip1tm2.1Rjd/Mapk8ip1tm2.1Rjd
B6.129S6-Mapk8ip1tm2.1Rjd 		normal growth/size/body region phenotype J:152617
normal homeostasis/metabolism phenotype J:152617
Mapk8ip1tm3.1Rjd/Mapk8ip1tm3.1Rjd
B6.129S6-Mapk8ip1tm3.1Rjd 		abnormal gluconeogenesis J:163808
abnormal liver morphology J:163808
decreased circulating leptin level J:163808
decreased food intake J:163808
decreased liver triglyceride level J:163808
decreased liver weight J:163808
decreased respiratory quotient J:163808
decreased susceptibility to diet-induced hepatic steatosis J:163808
increased insulin sensitivity J:163808
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory