Dio3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dio3
deiodinase, iodothyronine type III
MGI:1306782

19 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dio3^tm1Dmst/Dio3^tm1Dmst Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ involves: C57BL/6 * DBA	abnormal response to injury	J:218350
	normal growth/size/body region phenotype	J:218350
	normal homeostasis/metabolism phenotype	J:218350
	increased circulating thyroxine level	J:218350
	increased circulating triiodothyronine level	J:218350
	increased hepatocyte proliferation	J:218350
	normal liver/biliary system phenotype	J:218350
Dio3^tm1Stg/Dio3^tm1Stg involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal pituitary hormone level	J:105434
	abnormal thyroid hormone level	J:105434
	decreased circulating thyroid-stimulating hormone level	J:105434
	decreased circulating thyroxine level	J:105434
	decreased circulating triiodothyronine level	J:105434
	increased circulating thyroid-stimulating hormone level	J:105434
	increased triiodothyronine level	J:105434
	maternal imprinting	J:80434
	perinatal lethality, incomplete penetrance	J:105434
	postnatal growth retardation	J:105434
	prenatal lethality, incomplete penetrance	J:105434
	reduced fertility	J:105434

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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