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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
MGI:1298205
31 phenotypes from 4 alleles in 5 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Slc7a5em1(IMPC)H/Slc7a5+
C57BL/6NTac-Slc7a5em1(IMPC)H/H
increased basophil cell number J:211773
increased circulating potassium level J:211773
increased mean corpuscular volume J:211773
Slc7a5em1(IMPC)H/Slc7a5em1(IMPC)H
C57BL/6NTac-Slc7a5em1(IMPC)H/H
preweaning lethality, complete penetrance J:211773
Slc7a5tm1.1Daca/Slc7a5tm1.1Daca
Tg(Ckmm-cre)5Khn/?
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
abnormal amino acid level J:213820
increased gonadal fat pad weight J:213820
insulin resistance J:213820
Slc7a5tm1.1Daca/Slc7a5tm1.1Daca
Tg(Tek-cre)12Flv/0
B6J.Cg-Slc7a5tm1.1Daca Tg(Tek-cre)12Flv
abnormal amino acid level J:238065
abnormal amino acid metabolism J:238065
abnormal behavior J:238065
abnormal CNS synaptic transmission J:238065
abnormal gait J:238065
abnormal inhibitory synapse morphology J:238065
abnormal miniature excitatory postsynaptic currents J:238065
abnormal social investigation J:238065
abnormal symmetric synapse morphology J:238065
abnormal synaptic bouton morphology J:238065
abnormal synaptic vesicle number J:238065
abnormal translation J:238065
decreased locomotor activity J:238065
decreased miniature inhibitory postsynaptic current frequency J:238065
decreased vertical activity J:238065
excessive vocalization J:238065
impaired coordination J:238065
increased phenylalanine level J:238065
increased serine level J:238065
kyphosis J:238065
limb grasping J:238065
motor developmental delay J:238065
normal nervous system phenotype J:238065
short stride length J:238065
Slc7a5tm1.2Daca/Slc7a5tm1.2Daca
involves: 129P2/OlaHsd * C57BL/6
embryonic lethality, complete penetrance J:213820
Slc7a5tm1Lex/Slc7a5tm1Lex
involves: 129S5/SvEvBrd * C57BL/6J
preweaning lethality, complete penetrance J:171883

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory