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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Atg5
autophagy related 5
MGI:1277186
13 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
\Atg5tm1.1Myok/\Atg5tm1.1Myok
\Col1a1tm3(tetO-Pou5f1,-Sox2,-Klf4,-Myc)Jae/\Col1a1+
involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N 		abnormal cell physiology J:205532
\Atg5tm1Myok/\Atg5tm1Myok
\Cnot3tm1.1Kjkb/\Cnot3tm1.1Kjkb
\Tg(Ckmm-cre)5Khn/0
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6 * FVB 		abnormal autophagosome formation J:260012
decreased cardiac muscle contractility J:260012
increased heart weight J:260012
premature death J:260012
prolonged QT interval J:260012
\Atg5tm1Myok/\Atg5tm1Myok
\Rhebtm1.1Otsu/\Rhebtm1.1Otsu
\Tg(Myh6-cre)2182Mds/0
involves: 129S/SvEv * C57BL/6J * FVB/N 		postnatal lethality, complete penetrance J:197831
\Atg5tm1Myok/\Atg5tm1Myok
\Tg(CAG-EGFP/Map1lc3b)53Nmz/0
\Tg(Cryaa-cre)10Mlr/0
involves: 129S/SvEv * C57BL/6 * DBA/2 * FVB/N 		abnormal lens fiber morphology J:198392
cataract J:198392
impaired autophagy J:198392
\Atg5tm1Nmz/\Atg5tm1Nmz
\Tg(CAG-EGFP/Map1lc3b)53Nmz/?
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal autophagosome formation J:140583
abnormal thymus morphology J:140583
abnormal thymus physiology J:140583
neonatal lethality, complete penetrance J:140583
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory