81 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tcf21em1(IMPC)Mbp/Tcf21+ C57BL/6NCrl-Tcf21em1(IMPC)Mbp/MbpMmucd	abnormal eye morphology	J:211773
	abnormal kidney morphology	J:211773
	abnormal ovary morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal spleen morphology	J:211773
	abnormal testis morphology	J:211773
	anophthalmia	J:211773
	edema	J:211773
	embryonic growth retardation	J:211773
	enlarged kidney	J:211773
	enlarged testis	J:211773
	increased circulating calcium level	J:211773
	microphthalmia	J:211773
	persistence of hyaloid vascular system	J:211773
	small spleen	J:211773
Tcf21em1(IMPC)Mbp/Tcf21em1(IMPC)Mbp C57BL/6NCrl-Tcf21em1(IMPC)Mbp/MbpMmucd	abnormal blood vessel morphology	J:211773
	abnormal placenta morphology	J:211773
	abnormal placenta vasculature	J:211773
	edema	J:211773
	microphthalmia	J:211773
	preweaning lethality, complete penetrance	J:211773
Tcf21tm1Eno/Tcf21tm1Eno involves: 129 * Black Swiss	abnormal branching involved in lung morphogenesis	J:64068
	abnormal kidney development	J:64068
	abnormal spleen development	J:64068
	absent pulmonary alveoli	J:64068
	absent spleen	J:64068
	cyanosis	J:64068
	impaired branching involved in ureteric bud morphogenesis	J:64068
	neonatal lethality, complete penetrance	J:64068
	pallor	J:64068
	pulmonary hypoplasia	J:64068
	renal glomerulus atrophy	J:64068
	renal hypoplasia	J:64068
	respiratory distress	J:64068
Tcf21tm1Jrt/Tcf21tm1Jrt involves: 129S1/Sv * 129X1/SvJ	abnormal branching involved in ureteric bud morphogenesis	J:55785
	abnormal glomerular capillary morphology	J:55785
	abnormal kidney development	J:55785
	abnormal kidney medulla morphology	J:55785
	abnormal kidney mesenchyme morphology	J:55785
	abnormal kidney vasculature morphology	J:55785
	abnormal lung epithelium morphology	J:55785
	abnormal lung vasculature morphology	J:55785
	abnormal ovary morphology	J:92051
	abnormal ovary topology	J:92051
	abnormal peritubular capillary morphology	J:55785
	abnormal podocyte foot process morphology	J:55785
	abnormal podocyte morphology	J:55785
	abnormal proximal convoluted tubule morphology	J:55785
	abnormal pulmonary acinus morphology	J:55785
	abnormal pulmonary alveolar sac morphology	J:55785
	abnormal renal glomerulus morphology	J:55785
	abnormal ureteric bud morphology	J:55785
	abnormal ureteric bud tip morphology	J:55785
	absent proximal convoluted tubule brush border	J:55785
	absent pulmonary alveoli	J:55785
	absent type II pneumocytes	J:55785
	decreased nephron number	J:55785
	decreased renal glomerulus number	J:55785
	delayed kidney development	J:55785
	dilated respiratory conducting tube	J:55785
	disorganized testis cords	J:92051
	ectopic ovary	J:92051
	hemopericardium	J:55785
	impaired branching involved in alveolar sac morphogenesis	J:55785
	impaired branching involved in bronchus morphogenesis	J:55785
	impaired branching involved in ureteric bud morphogenesis	J:55785
	neonatal lethality, complete penetrance	J:55785
	primary sex reversal	J:92051
	pulmonary hypoplasia	J:55785
	renal hypoplasia	J:55785
	respiratory distress	J:55785
	respiratory failure	J:55785
	secondary sex reversal	J:92051
	sex reversal	J:92051
	small gonad	J:92051
	small kidney	J:55785
	small lung	J:55785
	small lung lobe	J:55785
Tcf21tm2.1Seq/Tcf21tm1Jrt Tg(Nphs2-cre)1Seq/0 involves: 129S1/Sv * 129X1/SvJ	abnormal kidney morphology	J:217144
	abnormal kidney physiology	J:217144
	abnormal podocyte morphology	J:217144
	abnormal renal glomerular capsule morphology	J:217144
	abnormal renal glomerulus morphology	J:217144
	abnormal urine homeostasis	J:217144
	glomerulosclerosis	J:217144
	increased urine protein level	J:217144
	kidney atrophy	J:217144
	pale kidney	J:217144
	podocyte foot process effacement	J:217144
Tcf21tm2.1Seq/Tcf21tm1Jrt Wnt4tm2(EGFP/cre)Svo/Wnt4+ involves: 129S1/Sv * 129X1/SvJ	abnormal podocyte morphology	J:217144
	abnormal renal glomerulus morphology	J:217144
	small kidney	J:217144
Tcf21tm2Eno/Tcf21tm2Eno involves: 129 * Black Swiss	abnormal branching involved in lung morphogenesis	J:64068
	abnormal kidney development	J:64068
	abnormal spleen development	J:64068
	absent pulmonary alveoli	J:64068
	absent spleen	J:64068
	cyanosis	J:64068
	impaired branching involved in ureteric bud morphogenesis	J:64068
	neonatal lethality, complete penetrance	J:64068
	pallor	J:64068
	pulmonary hypoplasia	J:64068
	renal glomerulus atrophy	J:64068
	renal hypoplasia	J:64068
	respiratory distress	J:64068
Tcf21tm2Eno/Tcf21tm2Eno involves: 129 * C57BL/6	abnormal heart apex morphology	J:185552
	abnormal heart morphology	J:185552
	abnormal heart shape	J:185552
	hemopericardium	J:185552
	increased heart right atrium size	J:185552
	thin myocardium	J:185552
Tcf21tm3.1(cre/Esr1*)Eno/Tcf21+ involves: 129S6/SvEvTac * C57BL/6	no abnormal phenotype detected	J:178665
Tcf21tm3.1(cre/Esr1*)Eno/Tcf21tm3.1(cre/Esr1*)Eno involves: 129S6/SvEvTac * C57BL/6	neonatal lethality, complete penetrance	J:178665