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Wnt4tm2(EGFP/cre)Svo
Targeted Allele Detail
Summary
Symbol: Wnt4tm2(EGFP/cre)Svo
Name: wingless-type MMTV integration site family, member 4; targeted mutation 2, Seppo Vainio
MGI ID: MGI:4399121
Synonyms: Wnt4EGFPCre, Wnt4tm2(cre)Svo
Gene: Wnt4  Location: Chr4:137004946-137026812 bp, + strand  Genetic Position: Chr4, 69.8 cM
Alliance: Wnt4tm2(EGFP/cre)Svo page
Severe anomalies in the urogenital system in Wnt4tm2(EGFP/cre)Svo/Wnt4tm1Svo mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154784
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Wnt4tm2(EGFP/cre)Svo expression driven by 1 gene
    An EGFPcre and neo cassette were inserted into exon 1. (J:154784, J:173153)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wnt4 (mouse)
Summary of all recombinase alleles driven by Wnt4.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt4 Mutation:  20 strains or lines available
References
Original:  J:154784 Shan J, et al., Generation of an allele to inactivate Wnt4 gene function conditionally in the mouse. Genesis. 2009 Nov;47(11):782-8
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory