Wnt4^{tm2(EGFP/cre)Svo}
Targeted Allele Detail

Summary

• Symbol: Wnt4^{tm2(EGFP/cre)Svo}
• Name: wingless-type MMTV integration site family, member 4; targeted mutation 2, Seppo Vainio
• MGI ID: MGI:4399121
• Synonyms: Wnt4^EGFPCre, Wnt4^tm2(cre)Svo
• Gene: Wnt4 Location: Chr4:137004946-137026812 bp, + strand Genetic Position: Chr4, 69.8 cM
• Alliance: Wnt4^{tm2(EGFP/cre)Svo} page

Severe anomalies in the urogenital system in Wnt4^{tm2(EGFP/cre)Svo}/Wnt4^tm1Svo mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154784
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Wnt4^{tm2(EGFP/cre)Svo} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt4 (MGI:98957)

• An EGFPcre and neo cassette were inserted into exon 1. (J:154784, J:173153)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt4 (mouse) Summary of all recombinase alleles driven by Wnt4. Alliance mouse Wnt4 gene page

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt4 Mutation: 20 strains or lines available

References

• Original: J:154784 Shan J, et al., Generation of an allele to inactivate Wnt4 gene function conditionally in the mouse. Genesis. 2009 Nov;47(11):782-8
• All: 20 reference(s)