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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Per2
period circadian clock 2
MGI:1195265
49 phenotypes from 6 alleles in 7 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Per2M1Btlr/Per2+
C57BL/6J-Per2M1Btlr
shortened circadian behavior period J:101977
Per2M1Btlr/Per2M1Btlr
C57BL/6J-Per2M1Btlr
abnormal brain wave pattern J:101977
abnormal circadian behavior J:264638
delayed circadian behavior phase J:264638
shortened circadian behavior period J:101977
Per2tm1a(EUCOMM)Hmgu/Per2tm1a(EUCOMM)Hmgu
C57BL/6N-Per2tm1a(EUCOMM)Hmgu/H
abnormal bone mineralization J:165965
abnormal coat/hair pigmentation J:165965
increased circulating alkaline phosphatase level J:165965
Per2tm1Brd/Per2tm1Brd
involves: 129S7/SvEvBrd * C57BL/6
abnormal basal metabolism J:136165
abnormal body weight J:136165
abnormal circadian sleep/wake cycle J:89417
abnormal food intake J:136165
abnormal food preference J:136165
abnormal locomotor circadian rhythm J:56167
abnormal male preputial gland morphology J:79456
abnormal maternal behavior J:136165
abnormal pregnancy J:136165
absent estrous cycle J:136165
arrhythmic circadian behavior persistence J:56167
normal behavior/neurological phenotype J:56167, J:77340
decreased cellular sensitivity to gamma-irradiation J:79456
decreased litter size J:136165
early reproductive senescence J:136165
enhanced behavioral response to cocaine J:77340
enhanced conditioned place preference behavior J:77340
increased body weight J:136165
increased bone ossification J:163112
increased bone volume J:163112
increased incidence of tumors by ionizing radiation induction J:79456
increased lymphoma incidence J:79456
increased mortality induced by gamma-irradiation J:79456
normal nervous system phenotype J:56167
premature death J:79456
prolonged estrous cycle J:136165
pup cannibalization J:136165
reduced female fertility J:136165
salivary gland epithelial hyperplasia J:79456
shortened circadian behavior period J:56167
Per2tm1Ccl/Per2tm1Ccl
involves: 129 * C57BL/6
arrhythmic circadian behavior persistence J:79456
decreased cellular sensitivity to gamma-irradiation J:79456
increased salivary gland tumor incidence J:79456
salivary gland epithelial hyperplasia J:79456
shortened circadian behavior period J:79456
Per2tm1Drw/Per2tm1Drw
B6.129-Per2tm1Drw/J
abnormal blood vessel morphology J:208598
abnormal bone marrow cell morphology/development J:208598
abnormal hematopoietic stem cell physiology J:208598
abnormal nervous system morphology J:208598
abnormal retina morphology J:208598
abnormal retina vasculature morphology J:208598
decreased hematopoietic stem cell proliferation J:208598
improved glucose tolerance J:208598
increased hematopoietic stem cell number J:208598
Per2tm1Drw/Per2tm1Drw
involves: 129
abnormal circadian temperature homeostasis J:95746
abnormal sleep pattern J:95746
arrhythmic circadian behavior persistence J:69626
Per2tm1Jt/Per2tm1Jt
involves: 129S6/SvEvTac * C57BL/6J
no abnormal phenotype detected J:89256

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory