Prom1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Prom1
prominin 1
MGI:1100886

20 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ctnnb1^tm1Mmt/Ctnnb1⁺ Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ Prom1^{tm1(cre/ERT2)Gilb}/Prom1⁺ involves: 129S6/SvEvTac * 129X1/SvJ	increased intestinal adenocarcinoma incidence	J:144215
	premature death	J:144215
Prom1^{tm1.1(DTA)Toko}/Prom1^{tm1.1(DTA)Toko} B6.Cg-Prom1^{tm1.1(DTA)Toko}/Rbrc	decreased retina photoreceptor cell number	J:230988
	retina photoreceptor degeneration	J:230988
	thin retina inner nuclear layer	J:230988
	thin retina inner plexiform layer	J:230988
	thin retina outer nuclear layer	J:230988
	thin retina outer plexiform layer	J:230988
Prom1^{tm1.1(DTA)Toko}/Prom1^{tm1.1(DTA)Toko} involves: C57BL/6 * SJL	no abnormal phenotype detected	J:152390
Prom1^{tm1.1(DTA)Toko}/Prom1^{tm1.1(DTA)Toko} involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal cone electrophysiology	J:230988
	abnormal rod electrophysiology	J:230988
	decreased photoreceptor outer segment number	J:230988
	decreased retina photoreceptor cell number	J:230988
	disorganized photoreceptor outer segment	J:230988
	photoreceptor inner segment degeneration	J:230988
	photoreceptor outer segment degeneration	J:230988
	retina outer nuclear layer degeneration	J:230988
	retina photoreceptor degeneration	J:230988
	short photoreceptor outer segment	J:230988
	thin retina outer nuclear layer	J:230988
	thin retina outer plexiform layer	J:230988
Prom1^{tm1.1(DTA)Toko}/Prom1^{tm1.1(DTA)Toko} Tg(CAG-cre/Esr1)5Amc/0 involves: C57BL/6 CBA * SJL	ataxia	J:152390
	decreased body weight	J:152390
	increased brain apoptosis	J:152390

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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