About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pkd2
polycystin 2, transient receptor potential cation channel
MGI:1099818
11 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\Hdac5tm1Eno/\Hdac5+
\Pkd2tm2Som/\Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		kidney cyst J:158762
\Hdac5tm1Eno/\Hdac5tm1Eno
\Pkd2tm2Som/\Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		lethality throughout fetal growth and development, complete penetrance J:158762
\Mirc1tm1.1Tyj/\Mirc1tm1.1Tyj
\Pkd2tm3Som/\Pkd2tm3Som
\Tg(Pkhd1-cre)1Igr/0
involves: 129S4/SvJae * C57BL/6 		decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
kidney cyst J:244067
premature death J:244067
\Pde1aem1Cjwa/\Pde1aem1Cjwa
\Pkd2tm1Som/\Pkd2tm2Som
involves: 129 * C57BL/6J * C57BL/6N * SJL 		kidney cyst J:246596
\Pkd1tm1.1Pcha/\Pkd1+
\Pkd2tm1Som/\Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
\Pkd1tm1.1Pcha/\Pkd1tm1.1Pcha
\Pkd2tm1Som/\Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
\Pkd1tm1.1Pcha/\Pkd1tm1.1Pcha
\Pkd2tm1Som/\Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
premature death J:220561
\Pkd1tm1.1Pcha/\Pkd1tm1.1Pcha
\Pkd2tm2Som/\Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
\Pkd1tm1Som/\Pkd1+
\Pkd2tm2Som/\Pkd2+
involves: 129/Sv * C57BL/6 * SJL 		kidney cyst J:78422
liver cyst J:78422
\Pkd1l1rks/\Pkd1l1+
\Pkd2lrm4/\Pkd2+
C3.Cg-Pkd2lrm4 Pkd1l1rks 		no abnormal phenotype detected J:170490
\Pkd2tm2Som/\Pkd2+
\Pkhd1tm1Gwu/\Pkhd1tm1Gwu
involves: 129/Sv * C57BL/6J * SJL 		dilated renal tubule J:143394
kidney cyst J:143394
\Pkd2tm2Som/\Pkd2+
\Prkcshtm1Som/\Prkcshtm1Som
\Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
increased kidney weight J:188763
kidney cyst J:188763
\Pkd2tm2Som/\Pkd2+
\Sec63tm1Som/\Sec63tm1Som
\Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
kidney cyst J:188763
\Pkd2tm3Som/\Pkd2tm3Som
\Tg(Pkd1)248Som/0
\Tg(Pkhd1-cre)1Igr/0
involves: C57BL/6J * SJL/J 		kidney cyst J:188763
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory