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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pkd2
polycystin 2, transient receptor potential cation channel
MGI:1099818
11 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Hdac5tm1Eno/Hdac5+
Pkd2tm2Som/Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		kidney cyst J:158762
Hdac5tm1Eno/Hdac5tm1Eno
Pkd2tm2Som/Pkd2tm2Som
involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL 		lethality throughout fetal growth and development, complete penetrance J:158762
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
Pkd2tm3Som/Pkd2tm3Som
Tg(Pkhd1-cre)1Igr/0
involves: 129S4/SvJae * C57BL/6 		decreased circulating creatinine level J:244067
decreased kidney cell proliferation J:244067
kidney cyst J:244067
premature death J:244067
Pde1aem1Cjwa/Pde1aem1Cjwa
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * C57BL/6N * SJL 		kidney cyst J:246596
Pkd1tm1.1Pcha/Pkd1+
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm1Som/Pkd2tm2Som
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
premature death J:220561
Pkd1tm1.1Pcha/Pkd1tm1.1Pcha
Pkd2tm2Som/Pkd2+
involves: 129 * C57BL/6J * SJL 		increased blood urea nitrogen level J:220561
increased kidney weight J:220561
polycystic kidney J:220561
Pkd1tm1Som/Pkd1+
Pkd2tm2Som/Pkd2+
involves: 129/Sv * C57BL/6 * SJL 		kidney cyst J:78422
liver cyst J:78422
Pkd1l1rks/Pkd1l1+
Pkd2lrm4/Pkd2+
C3.Cg-Pkd2lrm4 Pkd1l1rks 		no abnormal phenotype detected J:170490
Pkd2tm2Som/Pkd2+
Pkhd1tm1Gwu/Pkhd1tm1Gwu
involves: 129/Sv * C57BL/6J * SJL 		dilated renal tubule J:143394
kidney cyst J:143394
Pkd2tm2Som/Pkd2+
Prkcshtm1Som/Prkcshtm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
increased kidney weight J:188763
kidney cyst J:188763
Pkd2tm2Som/Pkd2+
Sec63tm1Som/Sec63tm1Som
Tg(Cdh16-cre)91Igr/0
involves: 129 * C57BL/6 * C57BL/6J * ICR * SJL 		increased blood urea nitrogen level J:188763
kidney cyst J:188763
Pkd2tm3Som/Pkd2tm3Som
Tg(Pkd1)248Som/0
Tg(Pkhd1-cre)1Igr/0
involves: C57BL/6J * SJL/J 		kidney cyst J:188763
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory