Pde1a^em1Cjwa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pde1a^em1Cjwa
• Name: phosphodiesterase 1A, calmodulin-dependent; endonuclease-mediated mutation 1, Christopher Ward
• MGI ID: MGI:6343412
• Synonyms: Pde1a^Del15
• Gene: Pde1a Location: Chr2:79664797-79959802 bp, - strand Genetic Position: Chr2, 47.64 cM, cytoband D
• Alliance: Pde1a^em1Cjwa page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The mutation is an in-frame 15bp deletion and insertion of a single A in exon 7. The 15bp in frame deletion (760_774) is predicted to remove amino acids FAAAI. (J:246596)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pde1a Mutation: 30 strains or lines available

References

• Original: J:246596 Wang X, et al., Generation and phenotypic characterization of Pde1a mutant mice. PLoS One. 2017;12(7):e0181087
• All: 1 reference(s)