73 phenotypes from 12 alleles in 14 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pkd2lrm4/Pkd2lrm4 C3.CAnN-Pkd2lrm4	abnormal direction of embryo turning	J:170490
	abnormal left-right axis patterning	J:170490
	dextrocardia	J:170490
	edema	J:170490
	normal embryo phenotype	J:170490
	lethality throughout fetal growth and development, complete penetrance	J:170490
	right pulmonary isomerism	J:170490
	right-sided stomach	J:170490
Pkd2lrm4/Pkd2lrm4 involves: BALB/cAnN * C3H/HeH	abnormal stomach position or orientation	J:145068
	dextrocardia	J:145068
	edema	J:145068
	left pulmonary isomerism	J:145068
	mesocardia	J:145068
	right pulmonary isomerism	J:145068
	situs inversus	J:145068
Pkd2m1Btlr/Pkd2m1Btlr C57BL/6J-Pkd2m1Btlr	abnormal kidney morphology	J:225044
	distended abdomen	J:225044
	polycystic kidney	J:225044
Pkd2tm1.1Gwu/Pkd2tm1.1Gwu Tg(Vil1-cre)997Gum/0 involves: C57BL/6 * C57BL/6J * SJL	abnormal kidney morphology	J:265516
	enlarged kidney	J:265516
	increased blood urea nitrogen level	J:265516
	increased circulating creatinine level	J:265516
	increased kidney cell proliferation	J:265516
	kidney cyst	J:265516
	kidney failure	J:265516
	liver cyst	J:265516
	pancreas cyst	J:265516
	premature death	J:265516
Pkd2tm1.1Tjwt/Pkd2tm1.1Tjwt involves: 129S/SvEv * 129X1/SvJ * C57BL/6 * SJL	no abnormal phenotype detected	J:165114
Pkd2tm1.1Tjwt/Pkd2tm1.1Tjwt Tg(Tek-cre)1Ywa/0 involves: 129S/SvEv * 129X1/SvJ * C57BL/6 * SJL	abnormal placenta vasculature	J:165114
	hemorrhage	J:165114
	normal homeostasis/metabolism phenotype	J:165114
	perinatal lethality, incomplete penetrance	J:165114
	polyhydramnios	J:165114
	prenatal lethality, incomplete penetrance	J:165114
Pkd2tm1.1Tjwt/Pkd2tm1.2Tjwt Meox2tm1(cre)Sor/Meox2+ involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	dextrocardia	J:165114
	edema	J:165114
	kidney cyst	J:165114
	neonatal lethality	J:165114
	pancreas cyst	J:165114
	situs inversus	J:165114
Pkd2tm1.2Tjwt/Pkd2tm1.2Tjwt involves: 129S/Sv * 129X1/SvJ * C57BL/6 * SJL	lethality throughout fetal growth and development, complete penetrance	J:165114
Pkd2tm1Dwo/Pkd2tm1Dwo either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal direction of embryo turning	J:77401
	abnormal heart development	J:77401
	abnormal heart looping	J:77401
	abnormal left-right axis patterning	J:77401
	abnormal liver development	J:77401
	abnormal lung development	J:77401
	abnormal pancreas morphology	J:77401
	absent spleen	J:77401
	embryonic lethality during organogenesis, complete penetrance	J:77401
	hemorrhage	J:77401
	hydrops fetalis	J:77401
	kidney cortex cyst	J:77401
	kidney cyst	J:77401
	pancreas cyst	J:77401
	situs ambiguus	J:77401
	situs inversus	J:77401
Pkd2tm1Gwu/Pkd2tm1Gwu involves: C57BL/6	abnormal hepatic vein morphology	J:143124
	abnormal liver morphology	J:143124
	abnormal papillary duct morphology	J:143124
	dilated bile duct	J:143124
	dilated pancreatic duct	J:143124
	dilated proximal convoluted tubule	J:143124
	dilated renal tubule	J:143124
	increased glomerular capsule space	J:143124
	kidney cyst	J:143124
	liver cyst	J:143124
	normal mortality/aging	J:143124
	pancreas cyst	J:143124
	postnatal growth retardation	J:143124
Pkd2tm1Sia/Pkd2tm1Sia Not Specified	abnormal primitive node morphology	J:195164
	embryonic lethality during organogenesis, incomplete penetrance	J:195164
	lethality throughout fetal growth and development, complete penetrance	J:195164
Pkd2tm1Som/Pkd2+ involves: 129/Sv * C57BL/6J * SJL	kidney cyst	J:47035
Pkd2tm1Som/Pkd2tm1Som involves: 129/Sv * C57BL/6J * SJL	kidney cortex cyst	J:47035
	kidney cyst	J:47035
	kidney medulla cyst	J:47035
	liver cyst	J:47035
Pkd2tm1Som/Pkd2tm2Som involves: 129/Sv * C57BL/6J * SJL	abnormal cholangiocyte morphology	J:158354
	abnormal cholangiocyte primary cilium morphology	J:158354
	bile duct proliferation	J:47035, J:158354
	enlarged kidney	J:158354
	enlarged liver	J:158354
	increased blood urea nitrogen level	J:59314, J:220561
	increased cholangiocyte apoptosis	J:158354
	increased kidney apoptosis	J:158354
	increased kidney cell proliferation	J:158354
	increased kidney weight	J:158354, J:220561
	increased liver weight	J:158354
	kidney failure	J:59314
	liver cyst	J:47035, J:158354
	liver fibrosis	J:158354
	pancreas cyst	J:59314
	polycystic kidney	J:47035, J:59314, J:158354, J:220561
	premature death	J:59314
Pkd2tm1Tjwt/Pkd2tm1Tjwt involves: 129S/SvEv * 129X1/SvJ	postnatal lethality, incomplete penetrance	J:165114
Pkd2tm2Som/Pkd2+ involves: 129/Sv * C57BL/6 * SJL	liver cyst	J:78422
Pkd2tm2Som/Pkd2+ involves: 129/Sv * C57BL/6J * SJL	kidney cyst	J:47035, J:59314
	liver cyst	J:47035, J:59314
	premature death	J:59314
Pkd2tm2Som/Pkd2tm2Som involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL	kidney cyst	J:158762
	lethality throughout fetal growth and development, complete penetrance	J:158762
Pkd2tm2Som/Pkd2tm2Som involves: 129/Sv * C57BL/6J * SJL	abnormal amniotic fluid composition	J:104483
	abnormal placental labyrinth vasculature morphology	J:104483
	abnormal primitive node morphology	J:107740
	atrial septal defect	J:59314
	atrioventricular septal defect	J:59314
	hemorrhage	J:59314
	hydrops fetalis	J:59314
	kidney cortex cyst	J:59314
	lethality throughout fetal growth and development, complete penetrance	J:59314
	pancreas cyst	J:59314
	pericardial effusion	J:59314
	polyhydramnios	J:104483
	ventricular septal defect	J:59314
Pkd2tm3Som/Pkd2tm3Som Tg(Pkhd1-cre)1Igr/0 involves: 129S4/SvJae * C57BL/6	enlarged kidney	J:244067
	increased blood urea nitrogen level	J:244067
	increased circulating creatinine level	J:244067
	increased kidney cell proliferation	J:244067
	polycystic kidney	J:244067
	premature death	J:244067
Pkd2tm3Som/Pkd2tm3Som Tg(Pkhd1-cre)1Igr/? Not Specified	abnormal mitotic spindle morphology	J:185863
	dilated kidney collecting duct	J:185863