Pik3r2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pik3r2
phosphoinositide-3-kinase regulatory subunit 2
MGI:1098772

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Kras^tm4Tyj/Kras⁺ Pik3r2^tm1Lca/Pik3r2^tm1Lca involves: 129S4/SvJae * 129S6/SvEvTac	increased lung tumor incidence	J:142254
Kras^tm4Tyj/Kras⁺ Pik3r1^tm1Lca/Pik3r1⁺ Pik3r2^tm1Lca/Pik3r2^tm1Lca involves: 129S4/SvJae * 129S6/SvEvTac	increased lung tumor incidence	J:142254
Kras^tm4Tyj/Kras⁺ Pik3r1^tm1Lca/Pik3r1^tm1Lca Pik3r2^tm1Lca/Pik3r2^tm1Lca involves: 129S4/SvJae * 129S6/SvEvTac	decreased lung tumor incidence	J:142254
Pik3r1^tm1Lca/Pik3r1^tm1Lca Pik3r2^tm1Lca/Pik3r2^tm1Lca Tg(Ckmm-cre)5Khn/0 involves: 129S6/SvEvTac * C57BL/6 * FVB	decreased heart weight	J:102176
	decreased myocardial fiber size	J:102176

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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