Stag2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stag2
STAG2 cohesin complex component
MGI:1098583

36 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Stag2^tm1.1Alos/Y involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal enterocyte proliferation	J:298088
	abnormal hematopoietic stem cell physiology	J:298088
	abnormal intestine morphology	J:298088
	abnormal mitosis	J:298088
	cellular necrosis	J:298088
	decreased body weight	J:298088
	decreased fibroblast proliferation	J:298088
	normal hematopoietic system phenotype	J:298088
	increased fibroblast apoptosis	J:298088
	normal neoplasm	J:298088
	premature death	J:298088
Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺ Stag2^tm1.1Alos/Stag2^tm1.1Alos involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal enterocyte proliferation	J:298088
	abnormal hematopoietic stem cell physiology	J:298088
	abnormal intestine morphology	J:298088
	abnormal mitosis	J:298088
	cellular necrosis	J:298088
	decreased body weight	J:298088
	decreased fibroblast proliferation	J:298088
	hematopoietic system phenotype	J:298088
	increased fibroblast apoptosis	J:298088
	neoplasm	J:298088
	premature death	J:298088
Stag2^tm1.1Alos/Y Tg(CAG-cre)1Nagy/0 involves: 129S6/SvEvTac * C57BL/6NCrl	abnormal cardiac outflow tract development	J:298088
	abnormal heart development	J:298088
	common atrium	J:298088
	decreased cell proliferation	J:298088
	decreased embryo size	J:298088
	decreased heart right ventricle size	J:298088
	embryonic growth retardation	J:298088
	embryonic lethality during organogenesis, complete penetrance	J:298088
Stag2^tm1.1Soga/Y Tg(Mx1-cre)1Cgn/0 involves: C57BL/6J * C57BL/6N * CBA/J	abnormal hematopoietic precursor cell morphology	J:289000
	abnormal hematopoietic stem cell physiology	J:289000
	abnormal hematopoietic system morphology/development	J:289000
	decreased B cell number	J:289000
	decreased common lymphocyte progenitor cell number	J:289000
	decreased erythroid progenitor cell number	J:289000
	decreased leukocyte cell number	J:289000
	decreased megakaryocyte-erythroid progenitor cell number	J:289000
	enlarged spleen	J:289000
	extramedullary hematopoiesis	J:289000
	increased common myeloid progenitor cell number	J:289000
	increased granulocyte monocyte progenitor cell number	J:289000
	increased granulocyte number	J:289000
	increased hematopoietic stem cell number	J:289000
	increased monocyte cell number	J:289000
	increased red blood cell distribution width	J:289000

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23