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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Jag1
jagged 1
MGI:1095416
39 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Dll1tm1Mjo/Dll1+
Jag1tm1Frad/Jag1+
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1 		normal renal/urinary system phenotype J:198632
Dll1tm1Mjo/Dll1+
Jag1tm1Frad/Jag1tm1Frad
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1 		absent podocytes J:198632
Dll1tm1Mjo/Dll1tm1Mjo
Jag1tm1Frad/Jag1+
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1 		abnormal nephron morphogenesis J:198632
decreased nephron number J:198632
Dll1tm1Mjo/Dll1tm1Mjo
Jag1tm1Frad/Jag1tm1Frad
Tg(Six2-EGFP/cre)1Amc/0
involves: 129/Sv * C57BL/6 * CD-1 		decreased nephron number J:198632
Jag1Mhdahtu/Jag1+
Six1Cwe/Six1+
C3HeB/FeJ-C3HeB/FeJ-Jag1Htu Six1Cwe 		abnormal crista ampullaris morphology J:149467
abnormal inner ear canal morphology J:149467
abnormal posterior semicircular canal morphology J:149467
abnormal superior semicircular canal morphology J:149467
circling J:149467
head bobbing J:149467
Jag1tm1.1Loo/Jag1+
Notch2tm1Grid/Notch2+
Tg(Alb1-cre)1Khk/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL 		no abnormal phenotype detected J:149131
Jag1tm1.1Vtlr/Jag1+
Notch1tm2Agt/Notch1+
involves: 129 		abnormal postnatal subventricular zone morphology J:103728
abnormal rostral migratory stream morphology J:103728
postnatal lethality, complete penetrance J:103728
Jag1tm1Frad/Jag1tm1Frad
Notch1tm1Agt/Notch1tm1Agt
Tg(Mx1-cre)1Cgn/0
involves: 129 * C57BL/6 * CBA 		normal hematopoietic system phenotype J:98129
Jag1tm1Frad/Jag1tm1Frad
Tg(Cdh5-cre)7Mlia/0
Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+
involves: 129 * 129S4/SvJaeSor * FVB/N 		abnormal atrioventricular cushion morphology J:189213
abnormal cardiac epithelial to mesenchymal transition J:189213
Jag1tm1Grid/Jag1+
Notch2tm1Grid/Notch2+
involves: 129S1/Sv 		abnormal bile duct development J:133171
abnormal bile duct morphology J:133171
Jag1tm1Grid/Jag1+
Notch2tm1Grid/Notch2+
involves: 129S1/Sv * C57BL/6J 		abnormal anterior eye segment morphology J:74574
abnormal bile duct development J:74574
abnormal glomerular capillary morphology J:67157
abnormal liver morphology J:74574
atrial septal defect J:74574
cholestasis J:74574
decreased renal glomerulus number J:74574
increased blood urea nitrogen level J:74574
increased circulating alanine transaminase level J:74574
increased circulating alkaline phosphatase level J:74574
jaundice J:74574
kidney microaneurysm J:74574
overriding aortic valve J:74574
postnatal growth retardation J:74574
postnatal lethality, incomplete penetrance J:74574
pulmonary artery stenosis J:74574
small kidney J:67157
ventricular hypoplasia J:74574
ventricular septal defect J:74574
Jag1tm1Grid/Jag1+
Notch2tm3.1Grid/Notch2+
B6.129S1-Jag1tm1Grid Notch2tm3.1Grid 		abnormal bile duct morphology J:171432
abnormal biliary tract morphology J:171432
Jag1tm1Grid/Jag1+
Poglut1Gt(IST10323G11)Tigm/Poglut1+
B6.Cg-Jag1tm1Grid Poglut1Gt(IST10323G11)Tigm 		abnormal bile duct morphology J:171432
abnormal biliary tract morphology J:171432
Jag1tm1Grid/Cm
involves: 101/H * 129S1/Sv * C3H/He * C57BL/6 * FVB/N 		intracranial hemorrhage J:54907
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/09/2024
MGI 6.23 		The Jackson Laboratory