Slc4a2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Slc4a2
solute carrier family 4 (anion exchanger), member 2
MGI:109351

40 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Slc4a2^tm1Ges/Slc4a2^tm1Ges involves: 129S6/SvEvTac	abnormal osteoclast morphology	J:193823
Slc4a2^tm1Ges/Slc4a2^tm1Ges involves: 129S6/SvEvTac	abnormal osteoclast physiology	J:193823
Slc4a2^tm1Ges/Slc4a2^tm1Ges involves: 129S6/SvEvTac * Black Swiss	abnormal esophageal epithelium morphology	J:91617
	abnormal gastric chief cell morphology	J:91617
	abnormal gastric parietal cell morphology	J:91617
	abnormal skeleton development	J:91617
	abnormal stomach epithelium morphology	J:91617
	achlorhydria	J:91617
	aphagia	J:91617
	ataxia	J:91617
	deafness	J:91617
	decreased birth body size	J:91617
	dilated gastric gland	J:91617
	failure of tooth eruption	J:91617
	perinatal lethality, incomplete penetrance	J:91617
	postnatal growth retardation	J:91617
	postnatal lethality, incomplete penetrance	J:91617
	premature death	J:91617
Slc4a2^tm1Jmed/Slc4a2⁺ involves: 129P2/OlaHsd * FVB	no abnormal phenotype detected	J:88196
Slc4a2^tm1Jmed/Slc4a2^tm1Jmed involves: 129P2/OlaHsd * FVB	abnormal apoptosis	J:88196
	abnormal caput epididymis morphology	J:88196
	abnormal cauda epididymis morphology	J:88196
	abnormal corpus epididymis morphology	J:88196
	abnormal epididymis morphology	J:88196
	abnormal spermiogenesis	J:88196
	azoospermia	J:88196
	decreased Sertoli cell number	J:88196
	normal homeostasis/metabolism phenotype	J:88196
	male infertility	J:88196
	small testis	J:88196
	testis hypoplasia	J:88196
Slc4a2^tm2Ges/Slc4a2^tm2Ges Ctsk^tm1(cre)Ska/Ctsk⁺ involves: C57BL/6NCrlj * CBA/JNCrlj	abnormal bone marrow cavity morphology	J:193823
	abnormal long bone metaphysis morphology	J:193823
	abnormal long bone morphology	J:193823
	abnormal osteoclast morphology	J:193823
	abnormal osteoclast physiology	J:193823
	abnormal trabecular bone morphology	J:193823
	increased bone trabecula number	J:193823
	increased trabecular bone thickness	J:193823
	increased trabecular bone volume	J:193823
	osteopetrosis	J:193823
Slc4a2^tm2Ges/Slc4a2^tm2Ges Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * CBA	abnormal osteoclast morphology	J:193823
	abnormal osteoclast physiology	J:193823
	increased bone mass	J:193823

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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