Trim28 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Trim28
tripartite motif-containing 28
MGI:109274

39 phenotypes from 7 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Tg(Nr5a1-cre)2Klp/0 Trim28^tm1.1Ics/Trim28^tm1.1Ipc involves: 129S * 129S2/SvPas * C57BL/6J * DBA/2J	abnormal ovarian follicle morphology	J:327192
Tg(Nr5a1-cre)2Klp/0 Trim28^tm1.1Ipc/Trim28^tm1.1Ipc involves: 129S * 129S2/SvPas * C57BL/6J * DBA/2J	abnormal ovarian follicle morphology	J:327192
	normal cellular phenotype	J:327192
Trim28^chatwo/Trim28^chatwo either: C57BL/6-Trim28^chatwo or (involves: C57BL/6J * FVB/NJ)	abnormal digestive system development	J:178936
	abnormal ectoplacental cavity morphology	J:178936
	abnormal endoderm development	J:178936
	abnormal extraembryonic coelom morphology	J:178936
	abnormal extraembryonic tissue morphology	J:178936
	abnormal lateral plate mesoderm morphology	J:178936
	abnormal parietal yolk sac morphology	J:178936
	abnormal somatic mesoderm morphology	J:178936
	abnormal trophectoderm morphology	J:178936
	delayed allantois development	J:178936
	embryonic growth arrest	J:178936
	embryonic lethality, complete penetrance	J:178936
	open neural tube	J:178936
	short rostral-caudal axis	J:178936
Trim28^chatwo/Trim28^tm1.2Ipc involves: 129S2/SvPas * C57BL/6J	embryonic growth arrest	J:178936
	embryonic lethality, complete penetrance	J:178936
Trim28^MommeD9/Trim28⁺ involves: FVB/N	abnormal sex determination	J:142335
Trim28^MommeD9/Trim28⁺ involves: FVB/N	decreased litter size	J:142335
Trim28^MommeD9/Trim28^MommeD9 involves: FVB/N	embryonic growth arrest	J:142335
Trim28^MommeD9/Trim28^MommeD9 involves: FVB/N	embryonic lethality, complete penetrance	J:142335
Trim28^tm1.1Ics/Trim28^tm1.1Ics involves: 129S * C57BL/6J	prenatal lethality, complete penetrance	J:327192
Trim28^tm1.1Ipc/Trim28^tm1.1Ipc Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: 129S2/SvPas * C57BL/6 * SJL	abnormal spermatid morphology	J:170392
	abnormal spermiation	J:170392
	decreased litter size	J:170392
	decreased male germ cell number	J:170392
	decreased testis weight	J:170392
	oligozoospermia	J:170392
	reduced male fertility	J:170392
	normal reproductive system phenotype	J:170392
	testis degeneration	J:170392
Trim28^tm1.1Ipc/Trim28^tm1.2Ipc Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ involves: 129S2/SvPas * C57BL/6 * CBA	abnormal digestive system development	J:178936
	abnormal lateral plate mesoderm morphology	J:178936
	abnormal vitelline vasculature morphology	J:178936
	normal embryo phenotype	J:178936
	embryonic growth arrest	J:178936
	short rostral-caudal axis	J:178936
	wavy neural tube	J:178936
Trim28^tm1.2Ipc/Trim28^tm1.2Ipc involves: 129S2/SvPas * C57BL/6	abnormal endoderm development	J:62628
	abnormal extraembryonic endoderm formation	J:62628
	absent mesoderm	J:62628
	embryonic lethality between implantation and somite formation, complete penetrance	J:62628
Trim28^tm1Fca/Trim28^tm1.1Ipc Plekha5^{Tg(AMH-cre)1Flor}/Plekha5⁺ involves: 129S2/SvPas * C57BL/6 * SJL	normal reproductive system phenotype	J:170392
Trim28^tm1Fca/Trim28^tm1Fca Not Specified	abnormal cell cycle	J:170392
	abnormal embryo turning	J:170392
	abnormal neural tube closure	J:170392
	embryonic growth retardation	J:170392
	embryonic lethality during organogenesis, complete penetrance	J:170392
Trim28^tm1Ipc/Trim28⁺ involves: 129S2/SvPas * C57BL/6	no abnormal phenotype detected	J:62628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23