Trim28tm1.2Ipc
Targeted Allele Detail
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Symbol: |
Trim28tm1.2Ipc |
Name: |
tripartite motif-containing 28; targeted mutation 1.2, Pierre Chambon |
MGI ID: |
MGI:1859550 |
Synonyms: |
L-, Tif1b-, TIF1beta- |
Gene: |
Trim28 Location: Chr7:12758079-12764959 bp, + strand Genetic Position: Chr7, 7.73 cM, cytoband A2
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Alliance: |
Trim28tm1.2Ipc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:62628
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Parent Cell Line: |
H1 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: Deletion of exons 4-14 of the coding region as follows: A PGK-neomycin cassette flanked by two loxP sites was introduced into intron 3 and a loxP site was introduced into exon 14. Mice positive for the presence of this allele were mated to CMV-Cre transgenic mice to generate mice in which the loxP flanked sequences were deleted.
(J:62628)
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Inheritance: |
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Recessive |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Trim28 Mutation: |
33 strains or lines available
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Original: |
J:62628 Cammas F, et al., Mice lacking the transcriptional corepressor TIF1beta are defective in early postimplantation development. Development. 2000 Jul;127(13):2955-63 |
All: |
5 reference(s) |
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