49 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atp7atm1.1Mjp/Y Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * C57BL/6	abnormal copper level	J:221066
	abnormal gait	J:221066
	abnormal gonadal fat pad morphology	J:221066
	abnormal motor capabilities/coordination/movement	J:221066
	abnormal neuromuscular synapse morphology	J:221066
	decreased grip strength	J:221066
	decreased skeletal muscle mass	J:221066
	impaired coordination	J:221066
	limb grasping	J:221066
	motor neuron degeneration	J:221066
	muscular atrophy	J:221066
Dlg1tm1Rlh/Dlg1tm1Rlh Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal dendrite morphology	J:141127
Dsptm1Efu/Dsptm1Efu Mnx1tm4(cre)Tmj/Mnx1+ either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6)	abnormal sciatic nerve morphology	J:219630
	decreased nerve conduction velocity	J:219630
	delayed axon extension	J:219630
	delayed peripheral nervous system regeneration	J:219630
	impaired ability to fire action potentials	J:219630
Fgd4tm1Ics/Fgd4tm1Ics Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv	normal nervous system phenotype	J:190437
Gdap1tm1Ics/Gdap1tm1Ics Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv	normal nervous system phenotype	J:221297
Gfra1tm2Jmi/Gfra1tm2Jmi Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * 129X1/SvJ	decreased motor neuron number	J:132854
Gt(ROSA)26Sortm1(CAG-PLS3,-GFP)Bwir/Gt(ROSA)26Sor+ Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * 129S4/SvJae * BALB/cJ * C57BL/6	normal muscle phenotype	J:193844
	normal nervous system phenotype	J:193844
Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S/SvEv * 129S1/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:188352
Lrp4tm1.1Line/Lrp4tm1.1Line Mnx1tm4(cre)Tmj/Mnx1+ Tg(ACTA1-cre)79Jme/0 involves: 129S/SvEv * 129S1/Sv * C57BL/6 * C57BL/6J * SJL	abnormal motor neuron morphology	J:188352
	abnormal neuromuscular synapse morphology	J:188352
	cyanosis	J:188352
	neonatal lethality, complete penetrance	J:188352
Mapttm1(Ewsr1/Etv4)Arbr/Mapt+ Mnx1tm4(cre)Tmj/Mnx1+ involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6	abnormal axon extension	J:100886
Mnx1tm1Jhk/Mnx1tm1Jhk Isl2tm2Slp/Isl2tm2Slp involves: 129P2/OlaHsd * 129S1/Sv	abnormal axon guidance	J:89755
	abnormal motor neuron innervation pattern	J:89755
	abnormal motor neuron morphology	J:89755
Mnx1tm4(cre)Tmj/Mnx1+ Isl2tm1Arbr/Isl2+ involves: 129S7/SvEvBrd * C57BL/6J	abnormal motor neuron morphology	J:69623, J:76364
Mnx1tm4(cre)Tmj/Mnx1+ Mycbp2tm1Adia/Mycbp2tm1Adia involves: 129S1/Sv * C57BL/6	abnormal neuromuscular synapse morphology	J:125702
	perinatal lethality, incomplete penetrance	J:125702
	normal respiratory system phenotype	J:125702
Mnx1tm4(cre)Tmj/Mnx1+ Rettm2(RET)Heno/Rettm2(RET)Heno involves: 129S1/Sv * C57BL/6 * SJL	normal nervous system phenotype	J:132854
Mnx1tm4(cre)Tmj/Mnx1+ Rettm2(RET)Heno/Rettm2(RET)Heno involves: C57BL/6 * SJL	abnormal motor neuron innervation pattern	J:132854
	decreased motor neuron number	J:132854
Mnx1tm4(cre)Tmj/Mnx1+ Tardbptm1.1Ckjs/Tardbptm1.2Cjks involves: 129S1/Sv * C57BL/6J	abnormal motor neuron morphology	J:190254
	abnormal spinal cord ventral horn morphology	J:190254
	astrocytosis	J:190254
	decreased body weight	J:190254
	impaired coordination	J:190254
	increased microglial cell activation	J:190254
	kyphosis	J:190254
	limb grasping	J:190254
	motor neuron degeneration	J:190254
	muscle weakness	J:190254
	muscular atrophy	J:190254
	premature death	J:190254
	weight loss	J:190254
Mnx1tm4(cre)Tmj/Mnx1+ Smn1tm1Cdid/Smn1tm1Cdid Grm7Tg(SMN2)89Ahmb/Grm7+ involves: 129 * 129S1/Sv * C57BL/6 * FVB	abnormal innervation	J:183080
	abnormal motor coordination/balance	J:183080
	abnormal righting response	J:183080
	normal behavior/neurological phenotype	J:183080
	decreased body weight	J:183080
	decreased heart rate	J:183080
	decreased motor neuron number	J:183080
	irregular heartbeat	J:183080
	lethargy	J:183080
	normal nervous system phenotype	J:183080
	postnatal lethality, complete penetrance	J:183080
	prolonged PR interval	J:183080
	prolonged QT interval	J:183080
Mnx1tm4(cre)Tmj/Mnx1+ Rhot1tm1.1Jmsu/Rhot1tm1.2Jmsu involves: 129 * 129S1/Sv * C57BL/6 * SJL	no abnormal phenotype detected	J:216408
Psmf1tm1c(EUCOMM)Hmgu/Psmf1tm1c(EUCOMM)Hmgu Mnx1tm4(cre)Tmj/Mnx1+ involves: 129S1/Sv * C57BL/6J * C57BL/6N	abnormal axon morphology	J:282431
	abnormal motor capabilities/coordination/movement	J:282431
	abnormal neuromuscular synapse morphology	J:282431
	axon degeneration	J:282431
	decreased body weight	J:282431
	kyphosis	J:282431
	muscular atrophy	J:282431