Mnx1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mnx1
motor neuron and pancreas homeobox 1
MGI:109160

22 phenotypes from 6 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mnx1^tm1Jhk/Mnx1^tm1Jhk involves: 129P2/OlaHsd	abnormal pancreas development	J:57314
	abnormal pancreatic beta cell physiology	J:57314
	abnormal pancreatic delta cell morphology	J:57314
	abnormal pancreatic islet morphology	J:57314
	decreased fetal size	J:57314
	decreased pancreatic beta cell number	J:57314
	normal immune system phenotype	J:57314
	neonatal lethality, complete penetrance	J:57314
	small pancreatic islets	J:57314
Mnx1^tm1Jhk/Mnx1^tm1Jhk involves: 129S1/Sv	abnormal axon guidance	J:89755
Mnx1^tm1Jhk/Mnx1^tm1Jhk involves: 129S1/Sv	abnormal innervation	J:89755
Mnx1^tm1Slp/Mnx1^tm1Slp involves: BALB/c * C57BL/6	no abnormal phenotype detected	J:152526
Mnx1^tm1Tmj/Mnx1^tm1Tmj involves: 129S1/Sv	abnormal axon morphology	J:57340
	abnormal duodenum morphology	J:57317
	abnormal motor neuron morphology	J:57340
	abnormal pancreas development	J:57317
	abnormal pancreatic islet morphology	J:57317
	decreased pancreatic beta cell number	J:57317
	decreased pancreatic delta cell number	J:57317
	neonatal lethality, complete penetrance	J:57340
	normal nervous system phenotype	J:57340
	primary atelectasis	J:57340
	thin diaphragm muscle	J:57340
Mnx1^tm2Tmj/Mnx1^tm2Tmj involves: 129S1/Sv	abnormal axon morphology	J:57340
	abnormal hypoglossal nerve morphology	J:57340
	abnormal motor neuron morphology	J:57340
	neonatal lethality, complete penetrance	J:57340
	normal nervous system phenotype	J:57340
	primary atelectasis	J:57340
	thin diaphragm muscle	J:57340
Mnx1^tm3Tmj/Mnx1^tm3Tmj involves: 129S1/Sv	abnormal axon morphology	J:57340
	abnormal motor neuron morphology	J:57340
	neonatal lethality, complete penetrance	J:57340
	normal nervous system phenotype	J:57340
	primary atelectasis	J:57340
	thin diaphragm muscle	J:57340
Mnx1^tm4(cre)Tmj/Mnx1⁺ involves: 129S1/Sv	abnormal neuromuscular synapse morphology	J:193844
Mnx1^tm4(cre)Tmj/Mnx1⁺ involves: 129S1/Sv	decreased skeletal muscle fiber size	J:193844

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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