94 phenotypes from 6 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Traf6tm1.1Mpa/Traf6tm1.1Mpa Lyz2tm1(cre)Ifo/Lyz2+ involves: 129P2/OlaHsd * C57BL/6	decreased circulating interleukin-6 level	J:145306
	decreased susceptibility to injury	J:145306
Traf6tm1Jino/Traf6tm1Jino involves: 129P2/OlaHsd * C57BL/6	abnormal coat/ hair morphology	J:77350
	abnormal hair follicle development	J:77350
	abnormal male preputial gland morphology	J:77350
	abnormal Meibomian gland development	J:77350
	abnormal osteoclast differentiation	J:77453
	abnormal sebaceous gland morphology	J:77350
	abnormal skin pigmentation	J:77350
	absent eccrine glands	J:77350
	absent guard hair	J:77350
	alopecia	J:77350
	decreased body size	J:77453
	decreased body weight	J:77453
	decreased immature B cell number	J:77453
	decreased lymph node number	J:77453
	failure of tooth eruption	J:77453
	kinked tail	J:77350
	osteopetrosis	J:77453
	postnatal growth retardation	J:77453
	postnatal lethality, complete penetrance	J:77453
	preweaning lethality, incomplete penetrance	J:77453
	small perianal sebaceous gland	J:77350
	translucent skin	J:77350
Traf6tm1Mak/Traf6tm1Mak involves: 129P3/J	abnormal long bone metaphysis morphology	J:54467
	abnormal long bone morphology	J:54467
	abnormal macrophage physiology	J:54467
	abnormal osteoclast morphology	J:54467
	abnormal osteoclast physiology	J:54467
	absent incisors	J:54467
	absent molars	J:54467
	decreased B cell proliferation	J:54467
	decreased body length	J:54467
	decreased body weight	J:54467
	decreased bone resorption	J:54467
	decreased circulating phosphate level	J:54467
	decreased length of long bones	J:54467
	decreased survivor rate	J:54467
	decreased tumor necrosis factor secretion	J:54467
	enlarged heart	J:54467
	enlarged liver	J:54467
	enlarged spleen	J:54467
	failure of tooth eruption	J:54467
	hypochromic anemia	J:54467
	increased bone mineral density	J:54467
	osteopetrosis	J:54467
	perinatal lethality, incomplete penetrance	J:54467
	postnatal lethality, incomplete penetrance	J:54467
	short femur	J:54467
Traf6tm1Ywc/Traf6tm1Ywc Not Specified	abnormal dendritic cell differentiation	J:85808
	abnormal dendritic cell physiology	J:85808
	abnormal lymph node morphology	J:85808
	abnormal spleen morphology	J:85808
	absent spleen white pulp	J:85808
	decreased body size	J:85808
	decreased dendritic cell number	J:85808
	decreased interleukin-6 secretion	J:85808
	decreased interleukin-12 secretion	J:85808
	enlarged spleen	J:85808
	osteopetrosis	J:85808
	postnatal lethality, complete penetrance	J:85808
	thymus atrophy	J:85808
Traf6tm2a(EUCOMM)Wtsi/Traf6+ C57BL/6N-Traf6tm2a(EUCOMM)Wtsi/Wtsi	increased grip strength	J:211773
Traf6tm2a(EUCOMM)Wtsi/Traf6tm2a(EUCOMM)Wtsi C57BL/6N-Traf6tm2a(EUCOMM)Wtsi/Wtsi	abnormal brain commissure morphology	J:239583
	abnormal brain morphology	J:239583
	abnormal coronary sinus connection	J:239583
	abnormal ductus venosus valve topology	J:239583
	abnormal endolymphatic sac topology	J:239583
	abnormal eye muscle morphology	J:239583
	abnormal forebrain morphology	J:239583
	abnormal kidney morphology	J:239583
	abnormal Mullerian duct morphology	J:239583
	abnormal myocardium compact layer morphology	J:239583
	abnormal olfactory bulb morphology	J:239583
	abnormal optic cup morphology	J:239583
	abnormal optic stalk morphology	J:239583
	abnormal stapes morphology	J:239583
	abnormal vertebral artery topology	J:239583
	abnormal vitelline vein topology	J:239583
	abnormal Wolffian duct morphology	J:239583
	absent ductus venosus valve	J:239583
	absent stapedial artery	J:239583
	bifid ureter	J:239583
	blood in lymph vessels	J:239583
	dilated bile duct	J:239583
	ductus venosus stenosis	J:239583
	exencephaly	J:239583
	herniated liver	J:239583
	intestinal/bowel diverticulum	J:239583
	multiple persisting craniopharyngeal ducts	J:239583
	muscular ventricular septal defect	J:239583
	perimembraneous ventricular septal defect	J:239583
	persistent right 6th pharyngeal arch artery	J:239583
	persistent right dorsal aorta	J:239583
	preweaning lethality, complete penetrance	J:211773
	subcutaneous edema	J:239583
	thin hypoglossal nerve	J:239583
	umbilical vein stenosis	J:239583
Traf6tm2Ywc/Traf6tm2Ywc Tg(Cd4-cre)1Cwi/? involves: C57BL/6 * DBA/2	abnormal lymphocyte anergy	J:130882
	increased activated T cell number	J:130882
	increased memory T cell number	J:130882