Pfkfb2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pfkfb2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
MGI:107815

7 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} Pfkfb2^tm1Ntang/Pfkfb2^tm1Ntang Sftpc^{tm1(cre/ERT2)Blh}/Sftpc⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal pulmonary alveolus epithelial cell morphology	J:353628
	abnormal vital capacity	J:353628
	decreased cellular ATP level	J:353628
	decreased lung compliance	J:353628
	decreased type I pneumocyte number	J:353628
	pulmonary fibrosis	J:353628
Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} Pfkfb2^tm2Ntang/Pfkfb2^tm2Ntang Sftpc^{tm1(cre/ERT2)Blh}/Sftpc⁺ involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal susceptibility to injury induced morbidity/mortality	J:353628
Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo}/Gt(ROSA)26Sor^{tm4(ACTB-tdTomato,-EGFP)Luo} Pfkfb2^tm2Ntang/Pfkfb2^tm2Ntang Sftpc^{tm1(cre/ERT2)Blh}/Sftpc⁺ Stk11^tm1.1Sjm/Stk11^tm1.1Sjm involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6	abnormal susceptibility to injury induced morbidity/mortality	J:353628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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