Ifnb1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Ifnb1
interferon beta 1, fibroblast
MGI:107657

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Ifnar1^tm1Agt/Ifnar1^tm1Agt Tg(H2-K1-Ifnb1)10Seif/Tg(H2-K1-Ifnb1)10Seif C3.Cg-Ifnar1^tm1Agt Tg(H2-K1-Ifnb1)10Seif	normal reproductive system phenotype	J:174828
Ifnb1^tm2.1Lien/Ifnb1^tm2.1Lien Tg(Itgax-cre)1-1Reiz/0 Tyr^c-2J/Tyr^c-2J involves: C57BL/6 * CBA	normal immune system phenotype	J:172226
Ifnb1^tm2.1Lien/Ifnb1^tm2.1Lien Tyr^c-2J/Tyr^c-2J involves: C57BL/6	normal immune system phenotype	J:172226
Ifnb1^tm2.1Lien/Ifnb1^tm2.1Lien Tyr^c-2J/Tyr^c-2J Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6	decreased circulating interferon-alpha level	J:172226
	decreased circulating interferon-beta level	J:172226
	decreased susceptibility to bacterial infection	J:172226

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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