57 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmp4tm2Blh/Bmp4+ Nogtm1Amc/Nog+ involves: 129S1/Sv * 129S6/SvEvTac	no abnormal phenotype detected	J:110617
Bmp4tm2Blh/Bmp4+ Nogtm1Amc/Nogtm1Amc involves: 129S1/Sv * 129S6/SvEvTac	abnormal vertebrae development	J:110617
	abnormal vertebral arch morphology	J:110617
	normal nervous system phenotype	J:110617
Bmp7tm1Kry/Bmp7tm1Kry Nogtm1Amc/Nogtm1Amc either: (involves: 129S1/Sv * C57BL/6) or (involves: 129S1/Sv * CD-1 * ICR)	normal digestive/alimentary phenotype	J:118341
	normal nervous system phenotype	J:118341
	prenatal lethality, complete penetrance	J:118341
Cer1tm1Belo/Cer1tm1Belo Nogtm1Amc/Nogtm1Amc involves: 129S1/Sv * 129X1/SvJ	abnormal basicranium morphology	J:74136
	abnormal frontal bone morphology	J:74136
	abnormal interparietal bone morphology	J:74136
	abnormal neural tube closure	J:74136
	abnormal occipital bone morphology	J:74136
	abnormal parietal bone morphology	J:74136
	absent tail	J:74136
	exencephaly	J:74136
	open neural tube	J:74136
	prenatal lethality	J:74136
	short limbs	J:74136
Chrdtm1Emdr/Chrdtm1Emdr Nogtm1Amc/Nogtm1Amc involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J	abnormal cephalic neural fold morphology	J:60303
	abnormal diencephalon morphology	J:60303
	abnormal direction of heart looping	J:60303
	abnormal facial morphology	J:60303
	abnormal forebrain development	J:60303
	abnormal left-right axis patterning	J:60303
	abnormal mesendoderm development	J:60303
	abnormal telencephalon morphology	J:60303
	absent mandible	J:60303
	absent nasal placodes	J:60303
	absent notochord	J:60303
	absent sclerotome	J:60303
	anophthalmia	J:60303
	aprosencephaly	J:60303
	cyclopia	J:60303
	decreased forebrain size	J:60303
	embryonic lethality between somite formation and embryo turning, incomplete penetrance	J:60303
	embryonic lethality during organogenesis, incomplete penetrance	J:60303
	holoprosencephaly	J:60303
	lethality throughout fetal growth and development, complete penetrance	J:60303
	proboscis	J:60303
	small pharynx	J:60303
	tracheoesophageal fistula	J:60303
Chrdtm1Emdr/Chrdtm1Emdr Nogtm1Amc/Nogtm1Amc involves: 129S1/Sv * 129X1/SvJ * ICR	abnormal direction of heart looping	J:137629
Grem1tm1Ecan/Grem1+ Nogtm1.1Rmh/Nogtm1.1Rmh Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL	abnormal neural tube morphology	J:169133
	decreased somite size	J:169133
	open neural tube	J:169133
Grem1tm1Ecan/Grem1tm1Ecan Nogtm1.1Rmh/Nogtm1.1Rmh Tmem163Tg(ACTB-cre)2Mrt/0 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N * SJL	abnormal brain development	J:169133
	abnormal head development	J:169133
	abnormal somite development	J:169133
	abnormal tail development	J:169133
	absent sclerotome	J:169133
	decreased somite size	J:169133
	kinked neural tube	J:169133
	open neural tube	J:169133
Nbl1tm1Rmh/Nbl1tm1Rmh Nogtm1Amc/Nogtm1Amc involves: 129P2/OlaHsd * 129S1/Sv * 129S6/SvEvTac	lumbar vertebral transformation	J:67351
Nodaltm1Rob/Nodal+ Nogtm1Amc/Nogtm1Amc involves: 129S/SvEv * 129S1/Sv	normal embryo phenotype	J:161524
Nogtm1Amc/Nog+ Smad3tm1Xfw/Smad3+ involves: 129/Sv * 129S1/Sv	abnormal embryonic tissue morphology	J:161524
Nogtm1Amc/Nog+ Smad3tm1Xfw/Smad3tm1Xfw involves: 129/Sv * 129S1/Sv	abnormal embryonic tissue morphology	J:161524
	holoprosencephaly	J:161524
Nogtm1Amc/Nogtm1Amc Smad3tm1Xfw/Smad3+ involves: 129/Sv * 129S1/Sv	abnormal anterior definitive endoderm morphology	J:161524
	abnormal embryonic tissue morphology	J:161524
	abnormal mesendoderm development	J:161524
	abnormal prechordal plate morphology	J:161524
	abnormal primitive streak formation	J:161524
	holoprosencephaly	J:161524
Nogtm1Amc/Nogtm1Amc Smad3tm1Xfw/Smad3tm1Xfw involves: 129/Sv * 129S1/Sv	abnormal embryonic tissue morphology	J:161524
	holoprosencephaly	J:161524
Tg(Krt14-Bmp4)#Jake/0 Tg(Krt14-Nog)#Jake/0 involves: BALB/c * C57BL/6 * FVB	abnormal enamel morphology	J:156471
	abnormal upper incisor morphology	J:156471
	interdigital webbing	J:78767
	normal limbs/digits/tail phenotype	J:78767