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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Alk
anaplastic lymphoma kinase
MGI:103305
9 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background
Annotated Term Reference
Alktm1.1(ALK*F1174L)Heno/Alk+
Tg(Mpz-cre)94Imeg/0
Tg(Th-MYCN)41Waw/0
involves: 129X1/SvJ * BALB/c * C57BL/6 * SJL
decreased tumor-free survival time J:294092
increased neuroblastoma incidence J:294092
Alktm1.1(ALK*F1174L)Heno/Alktm1.1(ALK*F1174L)Heno
involves: 129X1/SvJ * C57BL/6 * C57BL/6N * SJL
no abnormal phenotype detected J:294092
Alktm1.1(ALK*F1174L)Heno/Alktm1.1(ALK*F1174L)Heno
Tg(Mpz-cre)94Imeg/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6N * SJL
abnormal sympathetic ganglion morphology J:294092
enlarged superior cervical ganglion J:294092
normal neoplasm J:294092
Alktm1.1(ALK*F1174L)Heno/Alktm1.1(ALK*F1174L)Heno
Tg(Mpz-cre)94Imeg/0
Tg(Th-MYCN)41Waw/0
involves: 129X1/SvJ * BALB/c * C57BL/6 * SJL
decreased tumor latency J:294092
increased neuroblastoma incidence J:294092
premature death J:294092
Alktm1.1(ALK*F1174L)Heno/Alktm1.1(ALK*F1174L)Heno
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
involves: 129X1/SvJ * C57BL/6 * C57BL/6N * FVB/N * SJL
abnormal stellate ganglion morphology J:294092
normal neoplasm J:294092
Alktm1.1Ics/?
Tg(Th-MYCN)41Waw/0
involves: 129S2/SvPas * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6J
increased neuroblastoma incidence J:228124, J:261033
premature death J:261033
Alktm2.1Ics/?
Tg(Th-MYCN)41Waw/0
involves: 129S2/SvPas * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6J
increased neuroblastoma incidence J:228124, J:261033
premature death J:261033

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory