Atp7b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Atp7b
ATPase, Cu++ transporting, beta polypeptide
MGI:103297

38 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Atp7b^m1Btlr/Atp7b^m1Btlr C57BL/6J-Atp7b^m1Btlr	abnormal circulating bilirubin level	J:255002
Atp7b^tm1Tcg/Atp7b^tm1Tcg involves: 129S1/Sv	abnormal copper level	J:57632
	abnormal liver copper level	J:57632
	abnormal liver morphology	J:57632
	abnormal locomotor behavior	J:57632
	abnormal mammary gland physiology	J:57632
	ataxia	J:57632
	liver cirrhosis	J:57632
	normal liver/biliary system phenotype	J:57632
	postnatal growth retardation	J:57632
	postnatal lethality, incomplete penetrance	J:57632
	tremors	J:57632
Atp7b^tx-J/Atp7b^tx-J C3H/HeJ-Atp7b^tx-J/J	abnormal brain morphology	J:24233
	abnormal cerebral hemisphere morphology	J:24233
	abnormal frontal lobe morphology	J:24233
	abnormal liver morphology	J:86701, J:130273
	abnormal occipital lobe morphology	J:24233
	abnormal parietal lobe morphology	J:24233
	curly vibrissae	J:24233
	diluted coat color	J:24233
	increased brain copper level	J:86701
	increased eosinophil cell number	J:24233
	liver cirrhosis	J:24233
	maternal effect	J:24233
	neuron degeneration	J:24233
	postnatal lethality, incomplete penetrance	J:24233
Atp7b^tx/Atp7b^tx DL-Atp7b^tx	abnormal copper level	J:19226
	abnormal hepatocyte morphology	J:19226
	abnormal mineral level	J:19226
	abnormal muscle physiology	J:7102
	ataxia	J:7102
	curly vibrissae	J:7102
	decreased body weight	J:7102
	decreased circulating copper level	J:7102
	decreased liver copper level	J:7102
	diluted coat color	J:7102
	disheveled coat	J:7102
	normal endocrine/exocrine gland phenotype	J:66749
	hypopigmentation	J:7102
	increased brain copper level	J:19226
	increased circulating copper level	J:19226
	increased kidney copper level	J:19226
	increased liver copper level	J:7102, J:19226, J:40104
	liver cirrhosis	J:40104
	maternal effect	J:66749
	postnatal growth retardation	J:7102
	postnatal lethality, complete penetrance	J:7102
	reduced female fertility	J:7102
	tremors	J:7102
Atp7b^tx/Atp7b^tx involves: C57BL/6 * DL	abnormal muscle physiology	J:7102
	ataxia	J:7102
	curly vibrissae	J:7102
	decreased body weight	J:7102
	decreased circulating copper level	J:7102
	decreased liver copper level	J:7102
	diluted coat color	J:7102
	disheveled coat	J:7102
	hypopigmentation	J:7102
	increased liver copper level	J:7102
	postnatal growth retardation	J:7102
	postnatal lethality	J:7102
	reduced female fertility	J:7102
	tremors	J:7102

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