22 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atoh1tm2Hzo/Atoh1+ Gfi1tm1Sho/Gfi1tm1Sho involves: 129S1/Sv * C57BL/6J	abnormal cochlear hair cell morphology	J:80025
	abnormal vestibular hair cell morphology	J:80025
	abnormal vestibular hair cell stereociliary bundle morphology	J:80025
	cochlear hair cell degeneration	J:80025
Bmp2tm1Brd/Bmp2tm1.1Mis Gfi1tm1(cre)Gan/Gfi1+ involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	increased or absent threshold for auditory brainstem response	J:156945
Gfi1tm1(cre)Gan/Gfi1+ Rfx3tm2Wrth/Rfx3tm2Wrth involves: 129 * 129S7/SvEvBrd	normal hearing/vestibular/ear phenotype	J:227631
Gfi1tm1(cre)Gan/Gfi1+ Rfx1tm1.1Wrth/Rfx1tm1.1Wrth involves: 129S7/SvEvBrd	normal hearing/vestibular/ear phenotype	J:227631
Gfi1tm1(cre)Gan/Gfi1+ Rfx1tm1.1Wrth/Rfx1tm1.1Wrth Rfx3tm2Wrth/Rfx3tm2Wrth involves: 129 * 129S7/SvEvBrd	abnormal cochlear outer hair cell physiology	J:227631
	abnormal inner hair cell kinocilium morphology	J:227631
	absent cochlear outer hair cells	J:227631
	cochlear inner hair cell degeneration	J:227631
	deafness	J:227631
	decreased cochlear outer hair cell number	J:227631
	impaired hearing	J:227631
	increased apoptosis	J:227631
Gfi1tm1Wep/Gfi1tm1Wep Gfi1btm2Tmo/Gfi1btm2Tmo Tg(Mx1-cre)1Cgn/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	decreased hematopoietic stem cell number	J:167416
Gfi1tm5.1(GFI1*)Tmo/Gfi1+ involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal definitive hematopoiesis	J:192927
	abnormal mitosis	J:192927
Gfi1tm5.1(GFI1*)Tmo/Gfi1+ Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA	myeloid hyperplasia	J:192927
	premature death	J:192927
Gfi1tm5.1(GFI1*)Tmo/Gfi1tm5.1(GFI1*)Tmo involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal definitive hematopoiesis	J:192927
	abnormal mitosis	J:192927
	normal hematopoietic system phenotype	J:192927
	increased monocyte cell number	J:192927
Gfi1tm5.1(GFI1*)Tmo/Gfi1tm5.1(GFI1*)Tmo Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA	myeloid hyperplasia	J:192927
	premature death	J:192927
Gfi1tm6.1(GFI1)Tmo/Gfi1tm6.1(GFI1)Tmo Krastm4Tyj/Kras+ Tg(Mx1-cre)1Cgn/0 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA	myeloid hyperplasia	J:192927
	premature death	J:192927
Pkhd1l1tm2c(EUCOMM)Hmgu/Pkhd1l1tm2c(EUCOMM)Hmgu Gfi1tm1(cre)Gan/Gfi1+ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6N	prenatal lethality, complete penetrance	J:280240
Resttm1.1Bban/Rest+ Gfi1tm1(cre)Gan/Gfi1+ involves: 129S4/SvJaeSor * 129S7/SvEvBrd * FVB/N	cochlear inner hair cell degeneration	J:265659
	deafness	J:265659