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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Ube2b
ubiquitin-conjugating enzyme E2B
MGI:102944
34 phenotypes from 3 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background
Annotated Term Reference
Ube2btm1a(EUCOMM)Wtsi/Ube2b+
C57BL/6N-Ube2btm1a(EUCOMM)Wtsi/Ics
abnormal behavior J:165965
decreased circulating triglyceride level J:165965
increased circulating triglyceride level J:165965
Ube2btm1b(EUCOMM)Wtsi/Ube2b+
C57BL/6N-Ube2btm1b(EUCOMM)Wtsi/Ics
abnormal coat appearance J:211773
abnormal gait J:211773
decreased basophil cell number J:211773
decreased neutrophil cell number J:211773
enlarged heart J:211773
increased leukocyte cell number J:211773
increased lymphocyte cell number J:211773
limb grasping J:211773
Ube2btm1b(EUCOMM)Wtsi/Ube2btm1b(EUCOMM)Wtsi
C57BL/6N-Ube2btm1b(EUCOMM)Wtsi/Ics
preweaning lethality, incomplete penetrance J:211773
Ube2btm1Jhjh/Ube2btm1Jhjh
either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * FVB/N)
abnormal chiasmata formation J:81811
abnormal male meiosis J:81811
abnormal spermatocyte morphology J:81811
abnormal spermatogenesis J:81811
abnormal synaptonemal complex J:81811
abnormal telomere morphology J:81811
increased male germ cell apoptosis J:81811
male infertility J:81811
Ube2btm1Jhjh/Ube2btm1Jhjh
involves: 129 * C57BL/6
abnormal manchette morphology J:83771
abnormal outer dense fiber morphology J:83771
abnormal sperm fibrous sheath morphology J:83771
abnormal sperm flagellum morphology J:83771
abnormal spermatid morphology J:83771
ectopic manchette J:83771
Ube2btm1Jhjh/Ube2btm1Jhjh
involves: 129P2/OlaHsd
abnormal double-strand DNA break repair J:177475
Ube2btm1Jhjh/Ube2btm1Jhjh
involves: 129P2/OlaHsd * FVB/NJ
abnormal sperm head morphology J:35244
abnormal sperm midpiece morphology J:35244
abnormal spermatocyte morphology J:35244
abnormal spermatogenesis J:35244
asthenozoospermia J:35244
decreased testis weight J:35244
increased male germ cell apoptosis J:35244
male infertility J:35244
oligozoospermia J:35244
normal reproductive system phenotype J:35244
teratozoospermia J:35244

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory