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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524
23 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
\Atoh7tm1Gan/\Atoh7tm1Gan
\Pou4f2tm1Nat/\Pou4f2tm1Nat
B6.Cg-Pou4f2tm1Nat Atoh7tm1Gan
abnormal eye electrophysiology J:135827
abnormal Muller cell morphology J:135827
abnormal retina ganglion cell morphology J:135827
abnormal retina morphology J:135827
abnormal retina rod bipolar cell morphology J:135827
decreased amacrine cell number J:135827
decreased retina ganglion cell number J:135827
increased retina apoptosis J:135827
retina hypoplasia J:135827
thin retina ganglion layer J:135827
thin retina inner nuclear layer J:135827
thin retina outer nuclear layer J:135827
\Isl1tm1Gan/\Isl1tm2Gan
\Pou4f2tm1(ALPP)Whk/\Pou4f2tm2Whk
\Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2
optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
\Isl1tm2Gan/\Isl1tm2Gan
\Pou4f2tm1(ALPP)Whk/\Pou4f2tm2Whk
\Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2
optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
\Opn4tm1.1(cre)Saha/\Opn4tm1Yau
\Pou4f2tm4(DTA)Whk/\Pou4f2+
involves: 129S/SvEv * C57BL/6
abnormal innervation J:174940
abnormal olivary pretectal nucleus morphology J:174940
decreased retina ganglion cell number J:174940
\Pou4f1tm1.1Gan/\Pou4f1tm1.1Gan
\Pou4f2tm2.1Gan/\Pou4f2tm2.1Gan
\Tg(CAG-cre/Esr1*)5Amc/0
Not Specified
abnormal eye physiology J:215207
normal vision/eye phenotype J:215207
\Pou4f2tm3Whk/\Pou4f2tm3Whk
\Pou4f3tm1Whk/\Pou4f3tm1Whk
Not Specified
abnormal retina ganglion cell morphology J:73779
abnormal retina morphology J:73779
abnormal retina nerve fiber layer morphology J:73779
abnormal sensory neuron innervation pattern J:73779
abnormal vestibular system physiology J:73779
deafness J:73779
decreased retina ganglion cell number J:73779
increased amacrine cell number J:73779
thin retina ganglion layer J:73779

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory