Pou4f2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524

23 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Atoh7^tm1Gan/Atoh7^tm1Gan Pou4f2^tm1Nat/Pou4f2^tm1Nat B6.Cg-Pou4f2^tm1Nat Atoh7^tm1Gan	abnormal eye electrophysiology	J:135827
	abnormal Muller cell morphology	J:135827
	abnormal retina ganglion cell morphology	J:135827
	abnormal retina morphology	J:135827
	abnormal retina rod bipolar cell morphology	J:135827
	decreased amacrine cell number	J:135827
	decreased retina ganglion cell number	J:135827
	increased retina apoptosis	J:135827
	retina hypoplasia	J:135827
	thin retina ganglion layer	J:135827
	thin retina inner nuclear layer	J:135827
	thin retina outer nuclear layer	J:135827
Isl1^tm1Gan/Isl1^tm2Gan Pou4f2^tm1(ALPP)Whk/Pou4f2^tm2Whk Tg(Six3-cre)69Frty/? involves: 129S6/SvEvTac * C57BL/6 * DBA/2	optic nerve hypoplasia	J:134978
	retina ganglion cell degeneration	J:134978
Isl1^tm2Gan/Isl1^tm2Gan Pou4f2^tm1(ALPP)Whk/Pou4f2^tm2Whk Tg(Six3-cre)69Frty/? involves: 129S6/SvEvTac * C57BL/6 * DBA/2	optic nerve hypoplasia	J:134978
	retina ganglion cell degeneration	J:134978
Opn4^{tm1.1(cre)Saha}/Opn4^tm1Yau Pou4f2^tm4(DTA)Whk/Pou4f2⁺ involves: 129S/SvEv * C57BL/6	abnormal innervation	J:174940
	abnormal olivary pretectal nucleus morphology	J:174940
	decreased retina ganglion cell number	J:174940
Pou4f1^tm1.1Gan/Pou4f1^tm1.1Gan Pou4f2^tm2.1Gan/Pou4f2^tm2.1Gan Tg(CAG-cre/Esr1*)5Amc/0 Not Specified	abnormal eye physiology	J:215207
	normal vision/eye phenotype	J:215207
Pou4f2^tm3Whk/Pou4f2^tm3Whk Pou4f3^tm1Whk/Pou4f3^tm1Whk Not Specified	abnormal retina ganglion cell morphology	J:73779
	abnormal retina morphology	J:73779
	abnormal retina nerve fiber layer morphology	J:73779
	abnormal sensory neuron innervation pattern	J:73779
	abnormal vestibular system physiology	J:73779
	deafness	J:73779
	decreased retina ganglion cell number	J:73779
	increased amacrine cell number	J:73779
	thin retina ganglion layer	J:73779

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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