About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Pou4f2
POU domain, class 4, transcription factor 2
MGI:102524
23 phenotypes from multigenic genotypes
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
\Atoh7tm1Gan/\Atoh7tm1Gan
\Pou4f2tm1Nat/\Pou4f2tm1Nat
B6.Cg-Pou4f2tm1Nat Atoh7tm1Gan 		abnormal eye electrophysiology J:135827
abnormal Muller cell morphology J:135827
abnormal retina ganglion cell morphology J:135827
abnormal retina morphology J:135827
abnormal retina rod bipolar cell morphology J:135827
decreased amacrine cell number J:135827
decreased retina ganglion cell number J:135827
increased retina apoptosis J:135827
retina hypoplasia J:135827
thin retina ganglion layer J:135827
thin retina inner nuclear layer J:135827
thin retina outer nuclear layer J:135827
\Isl1tm1Gan/\Isl1tm2Gan
\Pou4f2tm1(ALPP)Whk/\Pou4f2tm2Whk
\Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
\Isl1tm2Gan/\Isl1tm2Gan
\Pou4f2tm1(ALPP)Whk/\Pou4f2tm2Whk
\Tg(Six3-cre)69Frty/?
involves: 129S6/SvEvTac * C57BL/6 * DBA/2 		optic nerve hypoplasia J:134978
retina ganglion cell degeneration J:134978
\Opn4tm1.1(cre)Saha/\Opn4tm1Yau
\Pou4f2tm4(DTA)Whk/\Pou4f2+
involves: 129S/SvEv * C57BL/6 		abnormal innervation J:174940
abnormal olivary pretectal nucleus morphology J:174940
decreased retina ganglion cell number J:174940
\Pou4f1tm1.1Gan/\Pou4f1tm1.1Gan
\Pou4f2tm2.1Gan/\Pou4f2tm2.1Gan
\Tg(CAG-cre/Esr1*)5Amc/0
Not Specified 		abnormal eye physiology J:215207
normal vision/eye phenotype J:215207
\Pou4f2tm3Whk/\Pou4f2tm3Whk
\Pou4f3tm1Whk/\Pou4f3tm1Whk
Not Specified 		abnormal retina ganglion cell morphology J:73779
abnormal retina morphology J:73779
abnormal retina nerve fiber layer morphology J:73779
abnormal sensory neuron innervation pattern J:73779
abnormal vestibular system physiology J:73779
deafness J:73779
decreased retina ganglion cell number J:73779
increased amacrine cell number J:73779
thin retina ganglion layer J:73779
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory