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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Nfatc2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
MGI:102463
28 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
Nfatc1tm1Rao/Nfatc1tm1Rao
Nfatc2tm1Rao/Nfatc2tm1Rao
Cd79atm1(cre)Reth/Cd79a+
involves: BALB/c
abnormal B cell physiology J:177319
decreased interleukin-2 secretion J:177319
Nfatc2tm1Glm/Nfatc2tm1Glm
Nfatc3tm1Glm/Nfatc3tm1Glm
involves: 129S2/SvPas
abnormal lymph node morphology J:51339
abnormal lymphocyte cell number J:51339
blepharitis J:51339
decreased T cell number J:51339
enlarged spleen J:51339
increased B cell number J:51339
increased inflammatory response J:51339
increased T cell number J:51339
interstitial pneumonia J:51339
postnatal growth retardation J:51339
Nfatc2tm1Glm/Nfatc2tm1Glm
Nfatc3tm1Glm/Nfatc3tm1Glm
Nfatc4tm1Grc/Nfatc4tm1Grc
involves: 129S2/SvPas
abnormal locomotor activation J:109139
abnormal sensory neuron innervation pattern J:83744
abnormal social/conspecific interaction behavior J:109139
abnormal spinal cord dorsal column morphology J:83744
abnormal trigeminal nerve morphology J:83744
decreased anxiety-related response J:109139
decreased embryo size J:83744
decreased grip strength J:109139
hypotonia J:109139
Nfatc2tm1Glm/Nfatc2tm1Glm
Nfatc4tm1Grc/Nfatc4tm1Grc
involves: 129S2/SvPas
abnormal cranium morphology J:109139
abnormal locomotor activation J:109139
abnormal mandible morphology J:109139
abnormal neurocranium morphology J:109139
abnormal social/conspecific interaction behavior J:109139
abnormal zygomatic arch morphology J:109139
decreased anxiety-related response J:109139
decreased grip strength J:109139
hypotonia J:109139
Nfatc2tm1Rao/Nfatc2tm1Rao
Nfatc3tm1Grc/Nfatc3tm1Grc
Tg(Lck-cre)I57Jxm/0
involves: ICR
abnormal double-negative T cell morphology J:141917
abnormal T cell differentiation J:141917
increased T cell apoptosis J:141917

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory