F2rl1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

F2rl1
F2R like trypsin receptor 1
MGI:101910

28 phenotypes from 6 alleles in 9 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
F2rl1^{tm1b(EUCOMM)Wtsi}/F2rl1^{tm1b(EUCOMM)Wtsi} C57BL/6N-F2rl1^{tm1b(EUCOMM)Wtsi}/J	increased startle reflex	J:211773
F2rl1^tm1Bpd/F2rl1^tm1Bpd B6.129P2-F2rl1^tm1Bpd	normal cardiovascular system phenotype	J:135087
	decreased susceptibility to endotoxin shock	J:88245
	normal immune system phenotype	J:88245
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd	abnormal thermal nociception	J:127006
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd * C57BL/6	abnormal pain threshold	J:124648
	decreased inflammatory response	J:124648
	increased inflammatory response	J:96196
	increased susceptibility to induced pancreatitis	J:96196
F2rl1^tm1Bpd/F2rl1^tm1Bpd involves: 129P2/OlaHsd * C57BL/6J	abnormal systemic arterial blood pressure	J:96312
	perinatal lethality, incomplete penetrance	J:96312
	postnatal lethality, incomplete penetrance	J:96312
F2rl1^tm1Cgh/F2rl1^tm1Cgh B6.129S4-F2rl1^tm1Cgh	decreased dendritic cell number	J:113591
F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae	abnormal skin physiology	J:111734, J:130935
F2rl1^tm1Cgh/F2rl1^tm1Cgh involves: 129S4/SvJae * C57BL/6	abnormal gallbladder physiology	J:123689
	abnormal glucose homeostasis	J:130781
	decreased susceptibility to injury	J:124303
	glomerulonephritis	J:124303
	normal immune system phenotype	J:132733
	impaired leukocyte tethering or rolling	J:76626
	improved glucose tolerance	J:130781
F2rl1^tm1Jkaw/F2rl1^tm1Jkaw involves: 129P2/OlaHsd * C57BL/6	decreased susceptibility to type IV hypersensitivity reaction	J:106127
F2rl1^tm1Mslb/F2rl1^tm1Mslb involves: 129X1/SvJ * C57BL/6	decreased IgE level	J:79757
F2rl1^tm1Mslb/F2rl1^tm1Mslb involves: 129X1/SvJ * C57BL/6	decreased inflammatory response	J:79757
F2rl1^tm1Wrf/F2rl1^tm1Wrf involves: 129P2/OlaHsd	abnormal physiological response to xenobiotic	J:81119, J:120751
	decreased circulating interleukin-18 level	J:102762
	liver inflammation	J:102762
F2rl1^tm1Wrf/F2rl1^tm1Wrf involves: 129P2/OlaHsd * C57BL/6	decreased physiological sensitivity to xenobiotic	J:81119
	decreased susceptibility to induced arthritis	J:81119
	increased cerebral infarct size	J:112482

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23